Myocardial contractility assessed by dynamic electrical impedance measurements during dobutamine stress
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Tipus de documentComunicació de congrés
Data publicació2015
EditorInstitute of Electrical and Electronics Engineers (IEEE)
Condicions d'accésAccés restringit per política de l'editorial
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Reconeixement-NoComercial-SenseObraDerivada 3.0 Espanya
Abstract
In this study, the electrical impedance of myocardial
tissue is measured dynamically during the cardial
cycle. The multisine-based approach used to perform electrical
impedance spectroscopy (EIS) measurements allows acquiring
complete spectral impedance information of the tissue dynamics
during contraction. Measurements are performed in situ in the
left ventricule of swines during contractility stress tests induced
by dobutamine infusion. Additionally, the ECG and the left
ventricular (LV) pressure are also acquired synchronously to
the impedance signals. The calculated impedance magnitude
exhibits a periodic behavior during tissue contraction. The
amplitude (peak-to-peak) of this signal is quantified and the
compared to the maximum first derivative of the LV pressure
(dP/dtmax) that is used as an indicator of contractility variations.
The results show a linear correlation between impedance
amplitude and dP/dtmax during dobutamine-increased contractility.
The present work demonstrates how fast EIS measurements
during heart contraction can represent a feasible method
to assess changes in myocardial contractility.
CitacióGarcía-Sánchez, T., Jorge, E., Amoros, G., Bragos, R., Cinca, J., Rosell, F. Myocardial contractility assessed by dynamic electrical impedance measurements during dobutamine stress. A: Annual International Conference of the IEEE Engineering in Medicine and Biology Society. "2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC 2015): Milan, Italy: 25-29 August 2015". Milan: Institute of Electrical and Electronics Engineers (IEEE), 2015, p. 6548-6551.
ISBN9781424492695
Versió de l'editorhttp://ieeexplore.ieee.org/xpls/abs_all.jsp?arnumber=7319893&tag=1
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07319893.pdf | 3,268Mb | Accés restringit |