The expression of AR by transfection in PC3 cells confers a less malignant phenotype by interfering with EGFR autophosphorylation and signalling in response to EGF leading to invasion through a mechanism involving an interaction between AR and EGFR.
The androgen receptor associates with the epidermal growth factor receptor in androgen-sensitive prostate cancer cells. / L. BONACCORSI ;M. MURATORI ;V. CARLONI ; S. MARCHIANI ; L. FORMIGLI; G. FORTI ; E. BALDI.. - In: STEROIDS. - ISSN 0039-128X. - STAMPA. - 38:(2004), pp. 549-552.
The androgen receptor associates with the epidermal growth factor receptor in androgen-sensitive prostate cancer cells..
BONACCORSI, LORELLA;MURATORI, MONICA;CARLONI, VINICIO;MARCHIANI, SARA;FORMIGLI, LUCIA;FORTI, GIANNI;BALDI, ELISABETTA
2004
Abstract
The expression of AR by transfection in PC3 cells confers a less malignant phenotype by interfering with EGFR autophosphorylation and signalling in response to EGF leading to invasion through a mechanism involving an interaction between AR and EGFR.
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