The homeopathic tincture of Taxes baccata L. is monographed in the current German Homeopathic Pharmacopoeia (HAB 2009). However, the described identification test is a common comparative TLC procedure that might be updated. The purpose of the current work was the quali-quantitative analysis by HPLC/DAD/MS of Taxus tincture. In this study we characterized polyphenolic compounds, in particular four hydroxycinnamic derivatives (0.85 mg/mL) and four flavonoids (quercetin and kaempferol 3-O-rutinoside and xylosyl glucosides); the total polyphenol content was 1.265 mg/mL of tincture. Starting from the official German Homeopathic Pharmacopoeia method of preparation, the aim of this work was to optimize a rapid and reproducible method for the analysis of herbal drugs and tincture, directly prepared in store or the herbalist's shop, to ensure safety and efficacy of the preparation. The procedure has to ensure validation, robustness of the results, and provide a quick response about the composition of compounds in the herbal drug preparation.

Quality control and analyses test method for Taxus Baccata L. tincture preparation / Vignolini P; Gehrmann B; Melzig M F; Borsacchi L; Scardigli A; Romani A. - In: NATURAL PRODUCT COMMUNICATIONS. - ISSN 1934-578X. - ELETTRONICO. - (2012), pp. 875-877.

Quality control and analyses test method for Taxus Baccata L. tincture preparation

VIGNOLINI, PAMELA;Borsacchi L;SCARDIGLI, ARIANNA;ROMANI, ANNALISA
2012

Abstract

The homeopathic tincture of Taxes baccata L. is monographed in the current German Homeopathic Pharmacopoeia (HAB 2009). However, the described identification test is a common comparative TLC procedure that might be updated. The purpose of the current work was the quali-quantitative analysis by HPLC/DAD/MS of Taxus tincture. In this study we characterized polyphenolic compounds, in particular four hydroxycinnamic derivatives (0.85 mg/mL) and four flavonoids (quercetin and kaempferol 3-O-rutinoside and xylosyl glucosides); the total polyphenol content was 1.265 mg/mL of tincture. Starting from the official German Homeopathic Pharmacopoeia method of preparation, the aim of this work was to optimize a rapid and reproducible method for the analysis of herbal drugs and tincture, directly prepared in store or the herbalist's shop, to ensure safety and efficacy of the preparation. The procedure has to ensure validation, robustness of the results, and provide a quick response about the composition of compounds in the herbal drug preparation.
2012
875
877
Vignolini P; Gehrmann B; Melzig M F; Borsacchi L; Scardigli A; Romani A
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Utilizza questo identificatore per citare o creare un link a questa risorsa: https://hdl.handle.net/2158/775504
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