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Inhibitory effect of tannins from galls of Carpinus tschonoskii on the degranulation of RBL-2H3 Cells
http://hdl.handle.net/2241/117707
http://hdl.handle.net/2241/1177075403d45e-b794-452e-823f-53f0ff64bbd5
名前 / ファイル | ライセンス | アクション |
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Cy_64-3_1.pdf (431.7 kB)
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Item type | Journal Article(1) | |||||
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公開日 | 2012-10-26 | |||||
タイトル | ||||||
タイトル | Inhibitory effect of tannins from galls of Carpinus tschonoskii on the degranulation of RBL-2H3 Cells | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | journal article | |||||
著者 |
Yamada, Parida
× Yamada, Parida× Ono, Takako× Shigemori, Hideyuki× Han, Junkyu× Isoda, Hiroko |
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著者別名 |
繁森, 英幸
× 繁森, 英幸× 韓, 畯奎× 礒田, 博子 |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | In this study, the anti-allergy potency of thirteen tannins isolated from the galls on buds of Carpinus tschonoskii (including two tannin derivatives) was investigated. RBL-2H3 (rat basophilic leukemia) cells were incubated with these compounds, and the release of β-hexosaminidase and cytotoxicity were measured. Of the thirteen tannins, tetragalloylglucose (2), pentagalloylglucose (3), casuarictin (4), and casuarinin (9) were the most potent inhibitors, and all the tannins showed no cytotoxic effect after 24 h of incubation. The results obtained suggest that tannins from C. tschonoskii are capable of inhibiting allergic reactions and may be useful for the treatment or prevention of type I allergic diseases. | |||||
書誌情報 |
Cytotechnology 巻 64, 号 3, p. 349-356, 発行日 2012-05 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0920-9069 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA10678299 | |||||
PubMed番号 | ||||||
識別子タイプ | PMID | |||||
関連識別子 | 22669603 | |||||
DOI | ||||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1007/s10616-012-9457-y | |||||
権利 | ||||||
権利情報 | © Springer Science+Business Media B.V. 2012 The original publication is available at www.springerlink.com |
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著者版フラグ | ||||||
値 | author | |||||
出版者 | ||||||
出版者 | Springer Science+Business Media B.V. | |||||
URI | ||||||
識別子 | http://hdl.handle.net/2241/117707 | |||||
識別子タイプ | HDL |