Un nouveau traitement de l’alopécie androgéno génétique les injections dans le cuir chevelu de plasma riche en plaquettes (PRP) autologue - Moreau - RMLg - 02-2021.pdf
[fr] L’alopécie androgéno-génétique se manifeste par une perte progressive des cheveux du sommet du
cuir chevelu, touchant aussi bien l’homme que la femme. Ses impacts sociaux et psychologiques négatifs sont souvent très importants. Elle peut se traiter par des médicaments (minoxidil topique, inhibiteurs de la 5α-réductase per os, oestroprogestatifs à visée anti-androgénique chez la femme), par des techniques chirurgicals d’autogreffes capillaires ou encore par photothérapie avec des lasers de basse énergie. Tous ces traitements ne sont pas dénués d’effets indésirables et leur efficacité n’est pas constante. Les injections sous-cutanées de plasma riche en plaquettes autologue dans le cuir chevelu peuvent constituer un traitement efficace de l’alopécie androgéno-génétique, en monothérapie ou comme adjuvant. Les modalités techniques, les modes d’action potentiels et les principaux résultats cliniques obtenus à ce jour sont présentés. [en] Androgenic alopecia is a genetically determined and leads to a progressive hair loss of the vertex, affecting both men and women. It is related to an important psychological and social distress. Medical therapies include topical minoxidil, oral 5α-reductase inhibitors and oestroprogestative drugs with anti-androgen effects for women. The surgical option is autograft hair transplantation. Recently, phototherapy with low-level energy lasers became available. All these treatments may present adverse effects and their effectiveness is questionable. Subcutaneous injections of autologous platelet-rich plasma into the scalp represent an interesting alternative treatment for androgenetic alopecia, as monotherapy or as an adjuvant treatment. The methodology, the possible mechanisms of action and some initial clinical results of this treatment are presented.
Disciplines :
Dermatology
Author, co-author :
MOREAU, Thomas; HFR-Riaz, Suisse > Service de Médecine interne
CASTRONOVO, Charlotte ; Centre Hospitalier Universitaire de Liège - CHU > Autres Services Médicaux > Service de dermatologie
Kaux, Jean-François ; Université de Liège - ULiège > Département des sciences de la motricité > Médecine physique, réadaptation et traumatologie du sport
Nikkels, Arjen ; Université de Liège - ULiège > Département des sciences cliniques > Dermatologie
PAQUET, Philippe ; Centre Hospitalier Universitaire de Liège - CHU > Autres Services Médicaux > Service de dermatologie
Language :
French
Title :
Un nouveau traitement de l’alopécie androgéno-génétique : les injections dans le cuir chevelu de plasma riche en plaquettes (PRP) autologue
Alternative titles :
[en] A new treatment for androgenetic alopecia : platelet-rich plasma injections
Publication date :
February 2021
Journal title :
Revue Médicale de Liège
ISSN :
0370-629X
eISSN :
2566-1566
Publisher :
Université de Liège. Revue Médicale de Liège, Liège, Belgium
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