Article (Scientific journals)
In Yarrowia lipolytica erythritol catabolism ends with erythrose phosphate
Niang, P. M.; Arguelles Arias, Anthony; Steels, Sébastien et al.
2020In Cell Biology International, 44 (2), p. 651-660
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Keywords :
Y. lipolytica; Erythritol; YALI0F01584g gene; YALI0F01628g gene; Yarrowia lipolytica
Abstract :
[en] In response to osmotic stress, the yeast Yarrowia lipolytica produces erythritol, a four-carbon sugar alcohol, from erythrose-P, an intermediate of the pentose phosphate pathway. Under non-stressing conditions (isotonic environment), the produced erythritol is subsequently recycled into erythrose-P that can feed the pentose phosphate pathway. Herein, gene YALI0F01584g was characterized as involved in the erythritol catabolic pathway. Several experimental evidences suggested that it encodes an erythrulose-1P isomerase that converts erythrulose-1P into erythrulose-4P. On the basis of our previous reports and results gathered in this study with genetically modified strains, including ΔYALI0F01584g and ΔYALI0F01628g disrupted mutants, the entire erythritol catabolic pathway has been characterized. © 2019 International Federation for Cell Biology
Disciplines :
Biotechnology
Author, co-author :
Niang, P. M.;  Microbial Processes and Interactions, TERRA Teaching and Research Center, University of Liège - Gembloux Agro-Bio Tech, Gembloux, 5030, Belgium
Arguelles Arias, Anthony ;  Microbial Processes and Interactions, TERRA Teaching and Research Center, University of Liège - Gembloux Agro-Bio Tech, Gembloux, 5030, Belgium
Steels, Sébastien ;  Université de Liège - ULiège > Département GxABT > Microbial, food and biobased technologies
Denies, Olivia ;  Université de Liège - ULiège > Département GxABT > Microbial, food and biobased technologies
Nicaud, J.-M.;  Micalis Institute, UMR1319, Team BIMLip: Integrative Metabolism of Microbial Lipids, INRA - AgroParisTech, Domaine de Vilvert, Jouy-en Josas, 78352, France
Fickers, Patrick ;  Université de Liège - ULiège > Département GxABT > Microbial, food and biobased technologies
Language :
English
Title :
In Yarrowia lipolytica erythritol catabolism ends with erythrose phosphate
Publication date :
2020
Journal title :
Cell Biology International
ISSN :
1065-6995
eISSN :
1095-8355
Publisher :
Wiley-Blackwell Publishing Ltd
Volume :
44
Issue :
2
Pages :
651-660
Peer reviewed :
Peer Reviewed verified by ORBi
Funders :
ULiège - Université de Liège [BE]
Available on ORBi :
since 18 February 2021

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