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| ファイル | 記述 | サイズ | フォーマット | |
|---|---|---|---|---|
| clpt.2011.38.pdf | 1.41 MB | Adobe PDF | 見る/開く |
| タイトル: | The use of induced pluripotent stem cells in drug development. |
| 著者: | Inoue, H    https://orcid.org/0000-0003-4736-9537 (unconfirmed)Yamanaka, S |
| 著者名の別形: | 井上, 治久 山中, 伸弥 |
| キーワード: | iPS cell drug development disease modeling control definition animal model personalized medicine |
| 発行日: | May-2011 |
| 出版者: | Nature Publishing Group |
| 誌名: | Clinical pharmacology and therapeutics |
| 巻: | 89 |
| 号: | 5 |
| 開始ページ: | 655 |
| 終了ページ: | 661 |
| 抄録: | Induced pluripotent stem cell (iPSC) technology is revolutionizing medical science, allowing the exploration of disease mechanisms and novel therapeutic molecular targets, and offering opportunities for drug discovery and proof-of-concept studies in drug development. This review focuses on the recent advancements in iPSC technology including disease modeling and control setting in its analytical paradigm. We describe how iPSC technology is integrated into existing paradigms of drug development and discuss the potential of iPSC technology in personalized medicine. |
| 著作権等: | © 2012 American Society for Clinical Pharmacology and Therapeutics This is not the published version. Please cite only the published version. この論文は出版社版でありません。引用の際には出版社版をご確認ご利用ください。 |
| URI: | http://hdl.handle.net/2433/160140 |
| DOI(出版社版): | 10.1038/clpt.2011.38 |
| PubMed ID: | 21430656 |
| 出現コレクション: | 学術雑誌掲載論文等 |
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