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yakushi.14-00227-2.pdf | 857.51 kB | Adobe PDF | 見る/開く |
タイトル: | 画像診断と治療の融合theranosticsのための放射性同位元素の利用 |
その他のタイトル: | Application of radioisotopes for theranostics, a combination of diagnostics and therapy |
著者: | 佐治, 英郎 |
著者名の別形: | Saji, Hideo |
キーワード: | radioisotope diagnosis therapy theranostics functional unit coupling radiopharmaceutical |
発行日: | 1-Apr-2015 |
出版者: | 日本薬学会 |
誌名: | Yakugaku zasshi |
巻: | 135 |
号: | 4 |
開始ページ: | 551 |
終了ページ: | 556 |
抄録: | Radioisotopes emit radiation with various characteristics. These characteristics have been used for various applications of radioisotopes in clinical fields. For example, diagnostic nuclear medicine is a technique that uses gamma-emitted radionuclides with high permeability into the body and can visualize changes in physiological and biochemical processes throughout the distributed and interrelated systems of living tissues and organs. Therapeutic nuclear medicine is a technique that uses beta-emitted radionuclides with high radiation damage to the cell and can be used for internal radiation therapy. Therefore, a strategy in which the same ligand is labeled with beta-emitted or gamma-emitted radioisotopes, i.e., a theranostics approach, is useful because an extensive availability of diagnostics and therapeutics is possible. In this presentation, some examples of a theranostics approach for radiolabeled compounds will be reported, including the results of our recent research. |
著作権等: | © 2015 by the PHARMACEUTICAL SOCIETY OF JAPAN |
URI: | http://hdl.handle.net/2433/200784 |
DOI(出版社版): | 10.1248/yakushi.14-00227-2 |
PubMed ID: | 25832834 |
出現コレクション: | 学術雑誌掲載論文等 |
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