ダウンロード数: 300
このアイテムのファイル:
ファイル | 記述 | サイズ | フォーマット | |
---|---|---|---|---|
jbm.b.33281.pdf | 836.54 kB | Adobe PDF | 見る/開く |
タイトル: | Comparison between alkali heat treatment and sprayed hydroxyapatite coating on thermally-sprayed rough Ti surface in rabbit model: Effects on bone-bonding ability and osteoconductivity. |
著者: | Kawai, Toshiyuki Takemoto, Mitsuru Fujibayashi, Shunsuke Tanaka, Masashi Akiyama, Haruhiko Nakamura, Takashi Matsuda, Shuichi |
著者名の別形: | 河井, 利之 |
キーワード: | titanium (alloys) hydroxy(1)lapatite bone ingrowth orthopaedic animal model |
発行日: | 20-Sep-2014 |
出版者: | wiley |
誌名: | Journal of biomedical materials research. Part B, Applied biomaterials |
巻: | 103 |
号: | 5 |
開始ページ: | 1069 |
終了ページ: | 1081 |
抄録: | In this study, we investigated the effect of different surface treatments (hydroxyapatite (HA) coating, alkali heat treatment, and no treatment) on the ability of bone to bond to a rough arc-sprayed Ti metal surface, using rabbit models. The bone-to-implant contacts for untreated, HA-coated, and alkali heat-treated implants were 21.2%, 72.1%, and 33.8% at 4 weeks, 21.8%, 70.9%, and 30.0% at 8 weeks, and 16.3%, 70.2%, and 29.9% at 16 weeks, respectively (n = 8). HA -coated implants showed significantly higher bone-to-implant contacts than the untreated and alkali heat-treated implants at all the time point, whereas alkali heat-treated implants showed significantly higher bone-to-implant contacts than untreated implants at 4 and 16 weeks. The failure loads in a mechanical test for untreated, HA coated, alkali heat-treated plates were 65.4 N, 70.7 N, and 90.8 N at 4 weeks, 76.1 N, 64.7 N, and 104.8 N at 8 weeks and 88.7 N, 92.6 N, and 118.5 N at 16 weeks, respectively (n = 8). The alkali heat-treated plates showed significantly higher failure loads than HA-coated plates at 8 and 16 weeks. The difference between HA-coated plates and untreated plates were not statistically significant at any time point. Thus HA coating, although it enables high bone-to-implant contact, may not enhance the bone-bonding properties of thermally-sprayed rough Ti metal surfaces. In contrast, alkali heat treatment can be successfully applied to thermally-sprayed Ti metal to enhance both bone-to-implant contact and bone-bonding strength. |
著作権等: | This is the peer reviewed version of the following article: Kawai T, Takemoto M, Fujibayashi S, Tanaka M, Akiyama H, Nakamura T, Matsuda S. 2015. Comparison between alkali heat treatment and sprayed hydroxyapatite coating on thermally-sprayed rough Ti surface in rabbit model: Effects on bone-bonding ability and osteoconductivity. J Biomed Mater Res Part B 2015:103B:1069–1081, which has been published in final form at http://dx.doi.org/10.1002/jbm.b.33281. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving. The full-text file will be made open to the public on 20 September 2015 in accordance with publisher's 'Terms and Conditions for Self-Archiving'. This is not the published version. Please cite only the published version. この論文は出版社版でありません。引用の際には出版社版をご確認ご利用ください。 |
URI: | http://hdl.handle.net/2433/201968 |
DOI(出版社版): | 10.1002/jbm.b.33281 |
PubMed ID: | 25242248 |
出現コレクション: | 学術雑誌掲載論文等 |
このリポジトリに保管されているアイテムはすべて著作権により保護されています。