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j.1552-6569.2008.00348.x.pdf | 822.82 kB | Adobe PDF | 見る/開く |
タイトル: | Signal Changes in the Brain on Susceptibility-Weighted Imaging Under Reduced Cerebral Blood Flow: A Preliminary Study |
著者: | Fushimi, Yasutaka https://orcid.org/0000-0002-1982-3168 (unconfirmed) Miki, Yukio Mori, Nobuyuki Okada, Tsutomu Urayama, Shin-ichi Fukuyama, Hidenao Togashi, Kaori |
著者名の別形: | 伏見, 育崇 富樫, かおり |
キーワード: | Susceptibility‐weighted imaging high‐field MRI hyperventilation |
発行日: | Jul-2010 |
出版者: | Wiley |
誌名: | Journal of Neuroimaging |
巻: | 20 |
号: | 3 |
開始ページ: | 255 |
終了ページ: | 259 |
抄録: | OBJECTIVES: To reveal the characteristics of susceptibility‐weighted imaging (SWI) under low cerebral blood flow (CBF) induced by hyperventilation (HV). MATERIALS AND METHODS: This study was approved by the institutional review board. Informed consent was obtained. Six healthy volunteers (5 men, 1 woman; mean age, 29 years; range, 24‐33 years) underwent SWI and arterial spin labeling perfusion imaging under normal ventilation (NV) and HV at 3.0 T. Regions of interest (ROIs) were placed on gray matter (GM) and white matter (WM) of the frontal lobe (FL) and occipital lobe (OL). Intensities of ROIs were compared between NV and HV. Contrast of veins compared with adjacent cerebral parenchyma (CV) was also compared between NV and HV. RESULTS: CBF during HV (CBFHV) was decreased compared with CBF during NV (CBFNV) (29.1 ± 4.6%). FL‐GMHV and OL‐GMHV showed significant signal decreases compared with FL‐GMNV and OL‐GMNV, respectively (P= .018, .017). CVHV was significantly increased compared with CVNV (164.1 ± 29.9%) (P= .00019). CONCLUSIONS: SWI sensitively reflects HV‐induced decreases in CBF. The present results might assist in the interpretation of SWI in clinical practice, since CBF decreases might also influence signal changes on SWI. |
著作権等: | This is the peer reviewed version of the following article: Journal of Neuroimaging, which has been published in final form at https://doi.org/10.1111/j.1552-6569.2008.00348.x. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. この論文は出版社版でありません。引用の際には出版社版をご確認ご利用ください。 This is not the published version. Please cite only the published version. |
URI: | http://hdl.handle.net/2433/261985 |
DOI(出版社版): | 10.1111/j.1552-6569.2008.00348.x |
PubMed ID: | 19220709 |
出現コレクション: | 学術雑誌掲載論文等 |
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