Please use this identifier to cite or link to this item:
https://hdl.handle.net/2440/131092
Citations | ||
Scopus | Web of Science® | Altmetric |
---|---|---|
?
|
?
|
Type: | Journal article |
Title: | Prescribing and deprescribing in chronic kidney disease |
Author: | Manski-Nankervis, J.-A. McMorrow, R. Nelson, C. Jesudason, S. Sluggett, J.K. |
Citation: | Australian Journal of General Practice, 2021; 50(4):183-187 |
Publisher: | Royal Australian College of General Practitioners |
Issue Date: | 2021 |
ISSN: | 2208-794X 2208-7958 |
Statement of Responsibility: | Jo-Anne Manski-Nankervis, Rita McMorrow, Craig Nelson, Shilpanjali Jesudason, Janet K Sluggett |
Abstract: | Background: Chronic kidney disease (CKD) rarely occurs in isolation; multimorbidity is the norm. As a result, polypharmacy is common in people with CKD. Some medications are indicated to reduce the risk of cardiovascular disease and progression of CKD. In contrast, some medications may require dose reduction or cessation as a result of advancing stages of CKD. Objective: The aim of this article is to describe broad principles of managing the challenges and necessities of polypharmacy in patients with CKD. Discussion: Medications such as angiotensin converting enzyme inhibitors, angiotensin receptor blockers, statins and sodium-glucose co-transporter-2 inhibitors may reduce cardiovascular disease risk and/or reduce CKD progression, and their use should be balanced by likelihood of benefit. Medication cessation or dose reduction may be required to prevent medication accumulation, adverse medication events and kidney injury. Polypharmacy can be addressed with a collaborative Home Medicines Review and use of deprescribing tools, using a shared decision-making approach. |
Keywords: | Humans Hydroxymethylglutaryl-CoA Reductase Inhibitors Polypharmacy Renal Insufficiency, Chronic Deprescriptions Multimorbidity |
Rights: | © The Royal Australian College of General Practitioners 2021 |
DOI: | 10.31128/ajgp-11-20-5752 |
Grant ID: | http://purl.org/au-research/grants/nhmrc/1168265 http://purl.org/au-research/grants/nhmrc/1156439 |
Published version: | http://dx.doi.org/10.31128/ajgp-11-20-5752 |
Appears in Collections: | Aurora harvest 4 Medicine publications |
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.