Adelaide Research & Scholarship
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https://hdl.handle.net/2440/18590
| Type: | Thesis |
| Title: | The role of the toxin-coregulated pilus in the pathogenesis of Vibrio cholerae 01 biotype El Tor / Elena Voss. |
| Author: | Voss, Elena |
| Issue Date: | 1995 |
| School/Discipline: | Dept. of Microbiology and Immunology |
| Abstract: | The major aim of this thesis is to establish whether toxin-coregulated pilus (TCP) is significant in the pathogenesis of Vibrio cholerae strains of the alternative El Tor biotype. The study investigates whether TCP are assembled by El Tor strains during growth in vitro, evaluates the in vivo significance of TCP by constructing tcpA mutants of several El Tor strains and comparing their in vivo behaviour with wild-type and determines whether the TCP produced by the 017 cosmid clones is solely cosmid-derived or whether the chromosomal tcp operon is also expressed. |
| Dissertation Note: | Thesis (Ph.D.)--University of Adelaide, Dept. of Microbiology and Immunology, 1996 |
| Subject: | Vibrio cholerae Genetics. Vaccines. |
| Description: | Includes bibliographical references. 146, [65] leaves, [18] leaves of plates : ill. ; 30 cm. |
| Provenance: | This electronic version is made publicly available by the University of Adelaide in accordance with its open access policy for student theses. Copyright in this thesis remains with the author. This thesis may incorporate third party material which has been used by the author pursuant to Fair Dealing exception. If you are the author of this thesis and do not wish it to be made publicly available or If you are the owner of any included third party copyright material you wish to be removed from this electronic version, please complete the take down form located at: http://www.adelaide.edu.au/legals |
| Appears in Collections: | Research Theses |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| 01front.pdf | 72.47 kB | Adobe PDF | View/Open | |
| 02whole.pdf | 10.67 MB | Adobe PDF | View/Open |
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