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https://hdl.handle.net/2440/36426
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Type: | Journal article |
Title: | Analysis of datasets showing which compounds kill which organisms: inferring two systems |
Author: | Hutchinson, T. |
Citation: | European Journal of Medicinal Chemistry, 2004; 39(1):107-111 |
Publisher: | Editions Scientifiques Medicales Elsevier |
Issue Date: | 2004 |
ISSN: | 0223-5234 1768-3254 |
Statement of Responsibility: | T. P. Hutchinson |
Abstract: | Experiments are sometimes conducted to show which of several compounds is successful at inactivating which of several microorganisms. This paper proposes a method of analysing the datasets obtained. The example refers to 33 compounds (2,4-dihydroxythiobenzanilides) and seven microorganisms (dermatophytes) [data from Eur. J. Med. Chem. 35 (2000) 393]. The conclusion is that two systems or modes of action are needed to explain the data. |
Keywords: | 2,4-Dihydroxythiobenzanilides antifungal activity dermatophytes data condensation |
Description: | Copyright © 2003 Elsevier SAS. All rights reserved. |
DOI: | 10.1016/j.ejmech.2003.11.006 |
Description (link): | http://www.elsevier.com/wps/find/journaldescription.cws_home/505813/description#description |
Published version: | http://dx.doi.org/10.1016/j.ejmech.2003.11.006 |
Appears in Collections: | Aurora harvest Centre for Automotive Safety Research publications |
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