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https://hdl.handle.net/2440/55490
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Type: | Journal article |
Title: | Effects of substrate hydrophobicity/hydrophilicity on the height measurement of individual DNA molecules. |
Author: | Wang, H. Zhou, X. An, H. Guo, Y. Sun, J. Zhang, Y. Hu, J. |
Citation: | Chinese Physics Letters, 2007; 24(3):644-647 |
Publisher: | Chinese Physical Soc |
Issue Date: | 2007 |
ISSN: | 0256-307X 1741-3540 |
Statement of Responsibility: | Wang, Hua-Bin; Zhou, Xing-Fei; An, Hong-Jie; Guo, Yun-Chang; Sun, Jie-Lin; Zhang, Yi and Hu, Jun |
Abstract: | Effects of substrate hydrophobicity/hydrophilicity on height measurement of individual ds-DNA molecules are investigated with tapping mode atomic force microscopy (TMAFM) and vibrating mode scanning polarization force microscopy (VSPFM). The measured heights of ds-DNA on hydrophobic highly oriented pyrolytic graphite (HOPG) are remarkably less than those on hydrophilic bare mica and Ni²⁺ treated mica in both TMAFM and VSPFM. By analysing the results, we propose that the hydrophobicity/hydrophilicity of substrate can greatly influence the height measurement of DNA molecules. |
DOI: | 10.1088/0256-307X/24/3/016 |
Published version: | http://dx.doi.org/10.1088/0256-307x/24/3/016 |
Appears in Collections: | Aurora harvest Earth and Environmental Sciences publications |
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