Research portfolio: study to investigate the remineralization potential of demineralized dentine under crowns.

Abstract

This research portfolio is submitted as part of the requirements for the degree Doctor of Clinical Dentistry. It consists of: Introduction: The section provides background information relating to the main research project. Literature review: This review summarises relevant information about dental hard tissues, dentinal tubules and fluid, cariology and the factors that influence recurrent caries associated with indirect restorations. Original research: This section includes: • An expanded version of the background to the reported work. • A manuscript ready for submission to an appropriate journal. The paper describes the effect of dentinal tubule fluid on demineralization and remineralization associated with fixed restorations in an in vitro experimental system. Draft manuscripts of four additional papers reporting associated work completed previously but not yet published are presented as background to the present study in the Appendix (for reference only). Discussion and conclusion: This section reviews the progress toward understanding the effect of dentinal tubule fluid on demineralization and remineralization and suggests areas for future investigation. Other scholarly work: This section includes electronic versions of all of the other scholarly work undertaken during the three years of the Doctor of Clinical Dentistry programme.