Please use this identifier to cite or link to this item:
https://hdl.handle.net/2440/74105
Citations | ||
Scopus | Web of Science® | Altmetric |
---|---|---|
?
|
?
|
Type: | Journal article |
Title: | Relation between beat-to-beat QT interval variability and t-wave amplitude in healthy subjects |
Author: | Hasan, M. Abbott, D. Baumert, M. |
Citation: | Annals of Noninvasive Electrocardiology, 2012; 17(3):195-203 |
Publisher: | Wiley-Blackwell Publishing |
Issue Date: | 2012 |
ISSN: | 1082-720X 1082-720X |
Statement of Responsibility: | Muhammad A. Hasan, Derek Abbott and Mathias Baumert |
Abstract: | OBJECTIVES: Elevated beat-to-beat QT interval variability (QTV) has been associated with increased cardiovascular morbidity and mortality. The aim of this study was to investigate interlead differences in beat-to-beat QTV of 12-lead ECG and its relationship with the T wave amplitude. METHODS: Short-term 12-lead ECGs of 72 healthy subjects (17 f, 38 ± 14 years; 55 m, 39 ± 13 years) were studied. Beat-to-beat QT intervals were extracted separately for each lead using a template matching algorithm. We calculated the standard deviation of beat-to-beat QT intervals as a marker of QTV as well as interlead correlation coefficients. In addition, we measured the median T-wave amplitude in each lead. RESULTS: There was a significant difference in the standard deviation of beat-to-beat QT intervals between leads (minimum: lead V3 (2.58 ± 1.36 ms), maximum: lead III (7.2 ± 6.4 ms), ANOVA: P < 0.0001). Single measure intraclass correlation coefficients of beat-to-beat QT intervals were 0.27 ± 0.18. Interlead correlation coefficients varied between 0.08 ± 0.33 for lead III and lead V1 and 0.88 ± 0.09 for lead II and lead aVR. QTV was negatively correlated with the T-wave amplitude (r = –0.62, P < 0.0001). There was no significant affect of mean heart rate, age or gender on QT variability (ANOVA: P > 0.05). CONCLUSIONS: QTV varies considerably between leads in magnitude as well as temporal patterns. QTV is increased when the T wave is small. |
Keywords: | Repolarization; QT interval; QT variability; electrocardiogram |
Rights: | © 2012, Wiley Periodicals, Inc. |
DOI: | 10.1111/j.1542-474X.2012.00508.x |
Grant ID: | http://purl.org/au-research/grants/arc/DP110102049 |
Published version: | http://dx.doi.org/10.1111/j.1542-474x.2012.00508.x |
Appears in Collections: | Aurora harvest 4 Electrical and Electronic Engineering publications |
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.