Please use this identifier to cite or link to this item:
https://hdl.handle.net/2440/82045
Citations | ||
Scopus | Web of Science® | Altmetric |
---|---|---|
?
|
?
|
Type: | Journal article |
Title: | Circulating microRNAs as biomarkers of prostate cancer: the state of play |
Author: | Sapre, N. Selth, L. |
Citation: | Prostate Cancer, 2013; 2013:1-10 |
Publisher: | Hindawi Publishing Corporation |
Issue Date: | 2013 |
ISSN: | 2090-3111 2090-312X |
Statement of Responsibility: | Nikhil Sapre and Luke A. Selth |
Abstract: | MicroRNAs are key regulators of gene expression and play critical roles in both normal physiology and pathology. Recent research has demonstrated that these molecules are present in body fluids, such as serum, plasma, and urine, and can be readily measured using a variety of techniques. More importantly, emerging evidence suggests that circulating or urine miRNAs are useful indicators of disease. Here, we consider the potential utility of such miRNAs as noninvasive biomarkers of prostate cancer, a disease that would benefit substantially from novel diagnostic and prognostic tools. The studies aimed at identifying diagnostic, prognostic, and/or predictive miRNAs for prostate cancer are summarised and reviewed. Finally, practical considerations that will influence the translation of this recent research into clinical implementation are discussed. |
Rights: | Copyright © 2013 Nikhil Sapre and Luke A. Selth. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
DOI: | 10.1155/2013/539680 |
Published version: | http://dx.doi.org/10.1155/2013/539680 |
Appears in Collections: | Aurora harvest Medicine publications |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
hdl_82045.pdf | Published version | 1.37 MB | Adobe PDF | View/Open |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.