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https://hdl.handle.net/2440/83457
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Type: | Journal article |
Title: | Evaluating long-term attachment of two different endoclips in the human gastrointestinal tract |
Author: | Swellengrebel, H. Marijnen, C. Vincent, A. Cats, A. |
Citation: | Gastrointestinal Endoscopy, 2010; 16(2):344-348 |
Publisher: | Mosby Inc |
Issue Date: | 2010 |
ISSN: | 0016-5107 1948-5190 |
Statement of Responsibility: | Hendrik Albert Maurits Swellengrebel, Cornelia Adriana Maria Marijnen, Andrew Vincent, Annemieke Cats |
Abstract: | <h4>Aim</h4>To evaluate the long-term attachment of two types of endoclips in the human gastrointestinal tract.<h4>Methods</h4>In this prospective observational study, endoclips were placed and followed-up during endoscopies or using fluoroscopic images as part of a prospective feasibility study evaluating external beam radiotherapy (EBRT, wk 1-3) followed by high dose rate brachytherapy (HDRBT with an endoluminal applicator once a week for 3 wk, wk 9-11) in medically inoperable rectal cancer patients. Initially, the type and number of endoclips were chosen randomly and later refined to 1 Resolution(®) clip (Microvasive) proximal and 2 Quickclips(®) (Olympus) distal to the tumor. Nine consecutive patients, included between September 2007 and August 2008 were analyzed. Retention rates were evaluated over three different observational periods [period 1: pre-HDRBT (wk -2-8), period 2: during HDRBT (wk 9-11) and period 3: post-HDRBT (wk 12-16)].<h4>Results</h4>In this study, a total of 44 clips were placed during endoscopy, either at the beginning or at the end of period 1. The Resolution clip had a higher overall retention rate than the Quickclip (P = 0.01). After a median period of 81 d after placement (in period 1), long-term retention rates for the Resolution clip and Quickclip clip were 67% and 35% respectively.<h4>Conclusion</h4>The Resolution clip has a high retention rate and is useful in situations where long-term attachment to the human gastrointestinal mucosa is warranted. |
Keywords: | Endoclip Radiotherapy Retention rate Cancer Delineation |
Rights: | ©2010 Baishideng Publishing Group Co., Limited. All rights reserved. |
DOI: | 10.4253/wjge.v2.i10.344 |
Published version: | http://dx.doi.org/10.4253/wjge.v2.i10.344 |
Appears in Collections: | Aurora harvest 4 Medicine publications |
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