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In Vivo Efficacy of Daptomycin against Methicillin-Resistant Staphylococcus aureus in a Mouse Model of Hematogenous Pulmonary Infection
http://hdl.handle.net/10069/35426
http://hdl.handle.net/10069/354265660885e-3972-4eca-a08e-f838fa0dd870
名前 / ファイル | ライセンス | アクション |
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ISYK688_Harada.pdf (1.2 MB)
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Item type | 学位論文 / Thesis or Dissertation(1) | |||||
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公開日 | 2015-05-28 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | In Vivo Efficacy of Daptomycin against Methicillin-Resistant Staphylococcus aureus in a Mouse Model of Hematogenous Pulmonary Infection | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | daptomycin | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | methicillin-resistant Staphylococcus aureus | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | hematogenous | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | pulmonary infection | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_db06 | |||||
資源タイプ | doctoral thesis | |||||
アクセス権 | ||||||
アクセス権 | open access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||
著者 |
原田, 陽介
× 原田, 陽介 |
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著者別名 | ||||||
姓名 | Harada, Yosuke | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Daptomycin is inactivated by pulmonary surfactant, but its effectiveness in hematogenous pulmonary infection has been poorly studied. The potential therapeutic application was evaluated in a methicillin-resistant Staphylococcus aureus (MRSA) hematogenous pulmonary infection mouse model. Compared with control results, daptomycin improved survival (P<0.001) and decreased the number of abscesses and bacteria in the lungs (P<0.01). Daptomycin may be an effective therapeutic option for MRSA hematogenous pulmonary infection. | |||||
内容記述 | ||||||
内容記述タイプ | Other | |||||
内容記述 | 長崎大学学位論文 学位記番号:博(医歯薬)甲第688号 学位授与年月日:平成26年3月20日 | |||||
内容記述 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Author: Harada Yosuke, Yanagihara Katsunori, Yamada Koichi, Migiyama Yohei, Nagaoka Kentaro, Morinaga Yoshitomo, Nakamura Shigeki, Imamura Yoshifumi, Hasegawa Hiroo, Miyazaki Taiga, Izumikawa Koichi, Kakeya Hiroshi, Kohno Shigeru | |||||
内容記述 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Citation: Antimicrobial Agents and Chemotherapy, 57(6), pp.2841-2844; 2013 | |||||
書誌情報 |
Antimicrobial Agents and Chemotherapy 巻 57, 号 6, p. 2841-2844, 発行日 2014-03-20 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 00664804 | |||||
EISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 10986596 | |||||
DOI | ||||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1128/AAC.02331-12 | |||||
権利 | ||||||
権利情報 | c 2013, American Society for Microbiology. | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
その他のタイトル | ||||||
その他のタイトル | 血行性MRSA肺感染マウスモデルにおけるダプトマイシンの有効性 | |||||
出版者 | ||||||
出版者 | American Society for Microbiology | |||||
関係URI | ||||||
識別子タイプ | HDL | |||||
関連識別子 | http://hdl.handle.net/10069/34637 | |||||
学位名 | ||||||
学位名 | 博士(医学) | |||||
学位授与機関 | ||||||
学位授与機関識別子Scheme | kakenhi | |||||
学位授与機関識別子 | 17301 | |||||
学位授与機関名 | Nagasaki University (長崎大学) | |||||
学位授与年月日 | ||||||
学位授与年月日 | 2014-03-20 | |||||
学位授与番号 | ||||||
学位授与番号 | 甲医歯薬第688号 | |||||
学位の種類 | ||||||
課程博士 | ||||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Nagasaki University (長崎大学), 博士(医学) (2014-03-20) |