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Experimental Study and Clinical Application of Polyglycolic Acid Sheet with Fibrin Glue for Oral Soft Tissue Surgery
http://hdl.handle.net/10069/37891
http://hdl.handle.net/10069/37891631c4402-0636-4c80-b68d-8510bde61ae2
名前 / ファイル | ライセンス | アクション |
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ISYK992_Inokuchi.pdf (2.2 MB)
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Item type | 学位論文 / Thesis or Dissertation(1) | |||||
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公開日 | 2017-11-17 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | Experimental Study and Clinical Application of Polyglycolic Acid Sheet with Fibrin Glue for Oral Soft Tissue Surgery | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Polyglycolic acid sheet | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Fibrin glue | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Oral surgery | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Scar shrinkage | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_db06 | |||||
資源タイプ | doctoral thesis | |||||
アクセス権 | ||||||
アクセス権 | open access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||
著者 |
井口, 聡
× 井口, 聡 |
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著者別名 | ||||||
姓名 | Inokuchi, Satoshi | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Objective: The purpose of the present study was to examine the effects of a Polyglycolic acid (PGA) sheet with fibrin glue in the prevention of scar shrinkage. Methods: A PGA sheet with fibrin glue was grafted into the tongue after partial glossectomy in 25 rabbits. The wounds were examined histologically and compared to those of animals without grafts at 1, 2, 4, and 8 weeks after surgery, with particular focus on the change in the shape of the tongue and scar shrinkage. Furthermore, a retrospective study was conducted for cases in which the material was grafted into the raw surface of the tongue after partial glossectomy in 20 patients with early tongue cancer or leukoplakia. Postoperative pain and bleeding, and functional disadvantages were compared between the patients with PGA grafts and 6 patients that received partial glossectomy followed by a collagen-based artificial dermis graft. Results: In the animal experiment, less scar shrinkage was observed in rabbits receiving the graft of the PGA sheet with fibrin glue than in those with an open wound. Clinical application of the PGA sheet with fibrin glue indicated that the materials could prevent postoperative pain and functional disadvantages compared to collagen-based artificial dermis, although no statistical analysis was conducted on these results because of a historical controlled study with a small number of patients. Conclusions: The results of this study suggest that a PGA sheet with fibrin glue is useful for treating an open wound after soft tissue surgery of the oral cavity. | |||||
内容記述 | ||||||
内容記述タイプ | Other | |||||
内容記述 | 長崎大学学位論文 学位記番号:博(医歯薬)甲第992号 学位授与年月日:平成29年9月6日 | |||||
内容記述 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Author: Satoshi Inokuchi, Satoshi Rokutanda, Souichi Yanamoto, Tomofumi Naruse, Yuki Sakamoto, Masahiro Umeda | |||||
内容記述 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Citation: Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology, 29(4), pp.295-300; 2017 | |||||
書誌情報 |
Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology 巻 29, 号 4, p. 295-300, 発行日 2017-09-06 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 22125558 | |||||
DOI | ||||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1016/j.ajoms.2017.02.006 | |||||
権利 | ||||||
権利情報 | c 2017 Asian AOMS, ASOMP, JSOP, JSOMS, JSOM, and JAMI. Published by Elsevier Ltd. All rights reserved. | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
その他のタイトル | ||||||
その他のタイトル | 口腔内軟組織手術にフィブリン糊とポリグリコール酸シートを使用した実験的研究と臨床応用 | |||||
出版者 | ||||||
出版者 | Elsevier Ltd. | |||||
関係URI | ||||||
識別子タイプ | HDL | |||||
関連識別子 | http://hdl.handle.net/10069/37803 | |||||
学位名 | ||||||
学位名 | 博士(歯学) | |||||
学位授与機関 | ||||||
学位授与機関識別子Scheme | kakenhi | |||||
学位授与機関識別子 | 17301 | |||||
学位授与機関名 | Nagasaki University (長崎大学) | |||||
学位授与年月日 | ||||||
学位授与年月日 | 2017-09-06 | |||||
学位授与番号 | ||||||
学位授与番号 | 甲医歯薬第992号 | |||||
学位の種類 | ||||||
課程博士 | ||||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Nagasaki University (長崎大学), 博士(歯学) (2017-09-06) |