Por favor, use este identificador para citar o enlazar a este item:
http://hdl.handle.net/10261/62092
COMPARTIR / EXPORTAR:
SHARE CORE BASE | |
Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL | DATACITE | |
Título: | Tripartite synapses: astrocytes process and control synaptic information |
Autor: | Perea, Gertrudis CSIC ORCID; Navarrete, Marta CSIC ORCID ; Araque, Alfonso CSIC ORCID | Fecha de publicación: | 2009 | Editor: | Elsevier | Citación: | Trends in Neurosciences 32: 421- 431 (2009) | Resumen: | The term 'tripartite synapse' refers to a concept in synaptic physiology based on the demonstration of the existence of bidirectional communication between astrocytes and neurons. Consistent with this concept, in addition to the classic 'bipartite' information flow between the pre- and postsynaptic neurons, astrocytes exchange information with the synaptic neuronal elements, responding to synaptic activity and, in turn, regulating synaptic transmission. Because recent evidence has demonstrated that astrocytes integrate and process synaptic information and control synaptic transmission and plasticity, astrocytes, being active partners in synaptic function, are cellular elements involved in the processing, transfer and storage of information by the nervous system. Consequently, in contrast to the classically accepted paradigm that brain function results exclusively from neuronal activity, there is an emerging view, which we review herein, in which brain function actually arises from the coordinated activity of a network comprising both neurons and glia. © 2009 Elsevier Ltd. All rights reserved. | URI: | http://hdl.handle.net/10261/62092 | DOI: | 10.1016/j.tins.2009.05.001 | Identificadores: | doi: 10.1016/j.tins.2009.05.001 issn: 0166-2236 |
Aparece en las colecciones: | (IC) Artículos |
Ficheros en este ítem:
Fichero | Descripción | Tamaño | Formato | |
---|---|---|---|---|
accesoRestringido.pdf | 15,38 kB | Adobe PDF | Visualizar/Abrir |
CORE Recommender
SCOPUSTM
Citations
1.258
checked on 15-mar-2024
WEB OF SCIENCETM
Citations
1.180
checked on 29-feb-2024
Page view(s)
758
checked on 18-mar-2024
Download(s)
267
checked on 18-mar-2024
Google ScholarTM
Check
Altmetric
Altmetric
NOTA: Los ítems de Digital.CSIC están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.