Item Details

title

Quorum Signaling and Biofilm Antibiotic Resistance Phenotypes of Nontypeable Haemophilus influenzae Clinical Isolates

author

Reimche, Jennifer

abstract

The genetically and phenotypically diverse bacterium nontypeable Haemophilus influenzae (NTHi) is a leading cause of otitis media (OM). This disease affects children around the world. Treatment is complicated by the ability of the bacteria to form biofilms in which they are more tolerant to antimicrobials. Developing a better understanding of biofilm antibiotic resistance and possible roles for cell-cell communication may lead to new therapeutic options. While many fascinating findings come from studies using NTHi lab strains, the results from any one strain do not necessarily represent the entire population.

subject

Antibiotics

Biofilm

Haemophilus influenzae

Quorum signaling

contributor

Swords, William E (committee chair)

Claiborne, Al (committee member)

Ornelles, David (committee member)

Richardson, Stephen (committee member)

Westcott, Marlena (committee member)

date

2015-08-25T08:35:39Z (accessioned)

2017-08-24T08:30:12Z (available)

2015 (issued)

degree

Microbiology & Immunology (discipline)

embargo

2017-08-24 (terms)

identifier

http://hdl.handle.net/10339/57274 (uri)

language

en (iso)

publisher

Wake Forest University

type

Dissertation