TRANSLATIONAL GENOMICS: THE IMPACT OF GENETIC RISK SCORE ON PATIENTS AND PHYSICIANS
Electronic Theses and Dissertations
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Item Details
- title
- TRANSLATIONAL GENOMICS: THE IMPACT OF GENETIC RISK SCORE ON PATIENTS AND PHYSICIANS
- author
- Turner, Aubrey Roland
- abstract
- Genomewide Association Studies have identified thousands of associations between genetic markers and complex disease risk. When several of these markers are used in combination, the predictive performance is strong; however, the clinical utility of multi-marker tests is not known. This thesis addresses a unifying question: Can genomic test results safely and effectively target healthcare decisions for patients and physicians?
- subject
- Genetic Counseling
- Genetic Risk Score
- Genetic Testing
- Prostate Cancer
- Prostate-Specific Antigen
- Randomized Controlled Trial
- contributor
- Xu, Jianfeng (committee chair)
- Hawkins, Gregory A (committee member)
- Howard, Timothy D (committee member)
- Meyers, Deborah A (committee member)
- Weaver, Kathryn E (committee member)
- date
- 2016-05-21T08:35:41Z (accessioned)
- 2017-05-20T08:30:08Z (available)
- 2016 (issued)
- degree
- Molecular Genetics & Genomics (discipline)
- embargo
- 2017-05-20 (terms)
- identifier
- http://hdl.handle.net/10339/59290 (uri)
- language
- en (iso)
- publisher
- Wake Forest University
- type
- Dissertation