Please use this identifier to cite or link to this item:
https://hdl.handle.net/10356/104212
Title: | Organocatalytic enantioselective γ-aminoalkylation of unsaturated ester : access to pipecolic acid derivatives | Authors: | Xu, Jianfeng Jin, Zhichao Chi, Robin Yonggui |
Keywords: | DRNTU::Science::Chemistry::Organic chemistry | Issue Date: | 2013 | Source: | Xu, J., Jin, Z., & Chi, Y. R. (2013). Organocatalytic Enantioselective γ-Aminoalkylation of Unsaturated Ester: Access to Pipecolic Acid Derivatives. Organic Letters, 15(19), 5028–5031. | Series/Report no.: | Organic letters | Abstract: | The direct γ-carbon functionalization of α,β-unsaturated esters via N-Heterocyclic Carbene (NHC) catalysis is disclosed. This catalytically generated nucleophilic γ-carbon undergoes highly enantioselective additions to hydrazones. The resulting δ-lactam products can be readily transformed to optically enriched pipecolic acid derivatives. | URI: | https://hdl.handle.net/10356/104212 http://hdl.handle.net/10220/19439 |
ISSN: | 1523-7060 | DOI: | 10.1021/ol402358k | Schools: | School of Physical and Mathematical Sciences | Rights: | © 2013 American Chemical Society. | Fulltext Permission: | none | Fulltext Availability: | No Fulltext |
Appears in Collections: | SPMS Journal Articles |
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