Título
The prostaglandin D2 receptor (PTGDR) gene in asthma and allergic diseases
Autor(es)
Palabras clave
Asthma
Atopy
Prostaglandin D(2)
Prostaglandin D(2) receptor
Clasificación UNESCO
3207.01 Alergias
2409 Genética
Fecha de publicación
2014-01
Editor
Elservier
Citación
García-Solaesa V, Sanz-Lozano C, Padrón-Morales J, Hernández-Hernández L, García-Sánchez A, Rivera-Reigada ML, Dávila-González I, Lorente-Toledano F, Isidoro-García M. The prostaglandin D2 receptor (PTGDR) gene in asthma and allergic diseases. Allergol Immunopathol (Madr). 2014 Jan-Feb;42(1):64-8. doi: 10.1016/j.aller.2012.12.002. Epub 2013 Feb 12. PMID: 23410912.
Resumen
[EN] The prostaglandin D2 receptor (PTGDR) gene has been associated to asthma and related phenotypes by linking and association studies. Functional studies involving animal models and other expression studies based on in vitro cell models also point to a possible role of polymorphisms in the promoter region, in the differential binding of transcription factors, and thus in PTGDR expression, which appear to be associated to the development of asthma or of susceptibility to the disease.
URI
ISSN
0301-0546
DOI
10.1016/j.aller.2012.12.002
Versión del editor
Aparece en las colecciones
