Título
Synthesis of trans‐β‐Elemene
Autor(es)
Palabras clave
Química orgánica
Anticancerosos
Radicales (Química)
Cloruros
Clasificación UNESCO
Fecha de publicación
2018
Editor
Wiley
Citación
Benito Iglesias, D., Herrero Teijón, P., Rubio González, R. & Fernández Mateos, A. (2018). Synthesis of trans‐β‐Elemene. European Journal of Organic Chemistry, 2018(35), 4926–4932. https://doi.org/10.1002/ejoc.201800800
Resumen
[EN]Highly efficient syntheses of the anti-cancer agent trans-β-elemene have been achieved by using the readily available (±)-limonene as starting material. The syntheses were achieved in only nine to eleven steps with good overall yields. The key step in these reaction sequences is a stereoselective radical cyclization, induced by titanocene chloride.
URI
ISSN
1434-193X
Versión del editor
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