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Antimicrobial effects of silver nanoparticles

Cited 3399 time in Web of Science Cited 3843 time in Scopus Download Rank4
Authors

Kim, Jun Sung; Kuk, Eunye; Yu, Kyeong Nam; Kim, Jong-Ho; Park, Sung Jin; Lee, Hu Jang; Kim, So Hyun; Park, Young Kyung; Park, Yong Ho; Hwang, Cheol Yong; Kim, Yong-Kwon; Lee, Yoon-Sik; Jeong, Dae Hong; Cho, Myung-Haing

Issue Date
2007-03-28
Publisher
Future Medicine
Citation
Nanomedicine 2007;3:95-101
Keywords
Ag nanoparticleAntimicrobial effects
Abstract
The antimicrobial effects of silver (Ag) ion or salts are well known, but the effects of Ag nanoparticles on microorganisms and antimicrobial mechanism have not been revealed clearly. Stable Ag nanoparticles were prepared and their shape and size distribution characterized by particle characterizer and transmission electron microscopic study. The antimicrobial activity of Ag nanoparticles was investigated against yeast, Escherichia coli, and Staphylococcus aureus. In these tests, Muller Hinton agar plates were used and Ag nanoparticles of various concentrations were supplemented in liquid systems. As results, yeast and E. coli were inhibited at the low concentration of Ag nanoparticles, whereas the growth-inhibitory effects on S. aureus were mild. The free-radical generation effect of Ag nanoparticles on microbial growth inhibition was investigated by electron spin resonance spectroscopy. These results suggest that Ag nanoparticles can be used as effective growth inhibitors in various microorganisms, making them applicable to diverse medical devices and antimicrobial control systems.
ISSN
1549-9634
Language
English
URI
https://hdl.handle.net/10371/8335
DOI
https://doi.org/10.1016/j.nano.2006.12.001
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