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In Vitro Validation of a Numerical Simulation of Leaflet Kinematics in a Polymeric Aortic Valve Under Physiological Conditions
journal contribution
posted on 2018-03-01, 00:00 authored by Saleh GharaieSaleh Gharaie, B Mosadegh, Y MorsiThis paper describes a computational method to simulate the non-linear structural deformation of a polymeric aortic valve under physiological conditions. Arbitrary Lagrangian-Eulerian method is incorporated in the fluid-structure interaction simulation, and then validated by comparing the predicted kinematics of the valve's leaflets to in vitro measurements on a custom-made polymeric aortic valve. The predicted kinematics of the valve's leaflets was in good agreement with the experimental results with a maximum error of 15% in a single cardiac cycle. The fluid-structure interaction model presented in this study can simulate structural behaviour of a stented valve with flexible leaflets, providing insight into the haemodynamic performance of a polymeric aortic valve.
History
Journal
Cardiovascular engineering and technologyVolume
9Issue
1Pagination
42 - 52Publisher
SpringerLocation
New York, N.Y.Publisher DOI
ISSN
1869-408XeISSN
1869-4098Language
engPublication classification
C1.1 Refereed article in a scholarly journal; C Journal articleCopyright notice
2018, Biomedical Engineering SocietyUsage metrics
Keywords
Computational fluid dynamicsFluid–structure interactionHeart valvesIn vitro experimental validationPolymeric aortic valvesScience & TechnologyLife Sciences & BiomedicineTechnologyCardiac & Cardiovascular SystemsEngineering, BiomedicalCardiovascular System & CardiologyEngineeringFluid-structure interactionMECHANICAL HEART-VALVEPARAMETRIC DESIGNPULSATILE FLOWHEMODYNAMICSIMPLANTATIONMechanical Engineering
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