A facile method for the preparation of bishomopropargylic alcohols from acyl chlorides
artículo original
Fecha
2014Autor
Vásquez Céspedes, Suhelen
Cabezas Pizarro, Jorge A.
Metadatos
Mostrar el registro completo del ítemResumen
Controlled dilithiation of propargyl bromide with two equivalents of n-butyllithium, in the presence of
TMEDA, produces the operational equivalent of the dianion 1,3-dilithiopropyne. The latter reacts
efficiently with acid chlorides to produce bishomopropargylic alcohols in a single step route and with
high regioselectivity and moderate yields.
External link to the item
10.1016/j.tetlet.2014.01.144Colecciones
- Química [360]