Iterative Otsu's method for OCT improved delineation in the aorta wall
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URI: http://hdl.handle.net/10902/10059DOI: 10.1117/12.2183720
ISBN: 978-1-62841-706-7
ISSN: 0277-786X
ISSN: 1996-756X
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Alonso Saro, Daniel; Real Peña, Eusebio; Val Bernal, José Fernando; Revuelta Soba, José Manuel; Pontón Cortina, Alejandro; Calvo Díez, Marta; Mayorga Fernández, Marta María; López Higuera, José Miguel; Conde Portilla, Olga MaríaFecha
2015Derechos
© 2015 Society of Photo-Optical Instrumentation Engineers and Optical Society of America. One print or electronic copy may be made for personal use only. Systematic reproduction and distribution, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.
Publicado en
Daniel Alonso, Eusebio Real, Jose F. Val-Bernal, José M. Revuelta, Alejandro Pontón, Marta Calvo Diez, Marta Mayorga, José M. López-Higuera, Olga M. Conde " Iterative Otsu's method for OCT improved delineation in the aorta wall ", in European Conference on Biomedical Optics: Optical Coherence Imaging Techniques and Imaging in Scattering Media, Brett E. Bouma, Maciej Wojtkowski, eds., Vol. 9541 of Proceedings of SPIE-OSA Biomedical Optics, 95411A (2015)
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SPIE Society of Photo-Optical Instrumentation Engineers -
The Optical Society (OSA)
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Palabras clave
OCT
Aortic wall degradation
Ascending thoracic aorta
Otsu’s method
Resumen/Abstract
Degradation of human ascending thoracic aorta has been visualized with Optical Coherence Tomography (OCT). OCT images of the vessel wall exhibit structural degradation in the media layer of the artery, being this disorder the final trigger of the pathology. The degeneration in the vessel wall appears as low-reflectivity areas due to different optical properties of acidic polysaccharides and mucopolysaccharides in contrast with typical ordered structure of smooth muscle cells, elastin and collagen fibers. An OCT dimension indicator of wall degradation can be generated upon the spatial quantification of the extension of degraded areas in a similar way as conventional histopathology. This proposed OCT marker can offer in the future a real-time clinical perception of the vessel status to help cardiovascular surgeons in vessel repair interventions. However, the delineation of degraded areas on the B-scan image from OCT is sometimes difficult due to presence of speckle noise, variable signal to noise ratio (SNR) conditions on the measurement process, etc. Degraded areas can be delimited by basic thresholding techniques taking advantage of disorders evidences in B-scan images, but this delineation is not optimum in the aorta samples and requires complex additional processing stages. This work proposes an optimized delineation of degraded areas within the aorta wall, robust to noisy environments, based on the iterative application of Otsu’s thresholding method. Results improve the delineation of wall anomalies compared with the simple application of the algorithm. Achievements could be also transferred to other clinical scenarios: carotid arteries, aorto-iliac or ilio-femoral sections, intracranial, etc.
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