Management of hyperinflammation in COVID-19 patients
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2022Derechos
Attribution 4.0 International
©The Author 2022. Published by Sociedad Española de Quimioterapia
Publicado en
Revista Española de Quimioterapia 2022; 35 (Suppl. 3): 6-9
Editorial
Sociedad española de quimioterapia
Enlace a la publicación
Palabras clave
COVID19
Corticosteroids
Tocilizumab
Immunomodulators
Resumen/Abstract
In response to SARS-CoV-2 infection, the immune system physiologically upregulates to try to clear the virus from the body; failure to compensate for this inflammatory response with an anti-inflammatory response leads to dysregulation of the immune system that ultimately leads to a situation of uncontrolled hyperinflammation called cytokine storm. This cytokine storm can cause ARDS or multi-organ failure leading to patient death. This review exposes the different mechanisms of the inflammatory response in COVID-19 infection and the therapeutic options to treat this process.
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