In this study, I use SCOT (Social Construction of Technology) theories to trace the history of lysergic acid diethylamide-25, which is commonly known as LSD. I show how the technological system of LSD corresponds to phases designated by SCOT theorist Thomas Hughes, specifically invention, development, innovation, growth, competition, and consolidation.

I explain the importance of Timothy Leary and the CIA in the social construction of the LSD system, and their influences on the transformation of LSD from a chemical technology to a highly controversial drug.

Finally, I discuss the fate of LSD research today, its usage among members of the public, especially youngsters, and the usefulness of SCOT theories for this study.