A lineage-specific Exo70 is required for receptor kinase-mediated immunity in barley

0562062 - ÚEB 2023 RIV US eng J - Článek v odborném periodiku
Holden, S. - Bergum, M. - Green, P.R. - Bettgenhaeuser, J. - Hernández-Pinzón, I. - Thind, A. - Clare, S. - Russell, J. M. - Hubbard, A. - Taylor, J. - Smoker, M. - Gardiner, M. - Civolani, L. - Cosenza, F. - Rosignoli, S. - Strugala, R. - Molnár, István - Šimková, Hana - Doležel, Jaroslav - Schaffrath, U. - Barrett, M. - Salvi, S. - Moscou, M. J.
A lineage-specific Exo70 is required for receptor kinase-mediated immunity in barley.
Science Advances. Roč. 8, č. 27 (2022), č. článku eabn7258. ISSN 2375-2548. E-ISSN 2375-2548
Grant CEP: GA MŠMT(CZ) EF16_019/0000827
Institucionální podpora: RVO:61389030
Klíčová slova: LEUCINE-RICH REPEAT * DISEASE RESISTANCE * EXOCYST
Obor OECD: Biochemistry and molecular biology
Impakt faktor: 13.6, rok: 2022
Způsob publikování: Open access
https://doi.org/10.1126/sciadv.abn7258

In the evolution of land plants, the plant immune system has experienced expansion in immune receptor and signaling pathways. Lineage-specific expansions have been observed in diverse gene families that are potentially involved in immunity but lack causal association. Here, we show that Rps8-mediated resistance in barley to the pathogen Puccinia striiformis f. sp. tritici (wheat stripe rust) is conferred by a genetic module: Pur1 and Exo70FX12, which are together necessary and sufficient. Pur1 encodes a leucine-rich repeat receptor kinase and is the ortholog of rice Xa21, and Exo70FX12 belongs to the Poales-specific Exo70FX clade. The Exo70FX clade emerged after the divergence of the Bromeliaceae and Poaceae and comprises from 2 to 75 members in sequenced grasses. These results demonstrate the requirement of a lineage-specific Exo70FX12 in Pur1-mediated immunity and suggest that the Exo70FX clade may have evolved a specialized role in receptor kinase signaling.
Trvalý link: https://hdl.handle.net/11104/0334478