Enantioselective β-Selective Addition of Isoxazolidin-5-ones to Allenoates Catalyzed by Quaternary Ammonium Salts

0575770 - ÚEB 2024 RIV DE eng J - Článek v odborném periodiku
Zebrowski, P. - Röser, K. - Chrenko, D. - Pospíšil, Jiří - Waser, M.
Enantioselective β-Selective Addition of Isoxazolidin-5-ones to Allenoates Catalyzed by Quaternary Ammonium Salts.
Synthesis. Roč. 55, č. 11 (2023), s. 1706-1713. ISSN 0039-7881. E-ISSN 1437-210X
Grant CEP: GA MŠMT(CZ) EF16_019/0000738
Institucionální podpora: RVO:61389030
Klíčová slova: allenoates * ammonium salt catalysis * heterocycles * organocatalysis * β-amino acids
Obor OECD: Organic chemistry
Impakt faktor: 2.6, rok: 2022
Způsob publikování: Open access
https://doi.org/10.1055/a-1948-5493

The enantioselective addition of isoxazolidin-5-ones to the β-carbon of allenoates has been carried out by using a novel spirobiindane-based quaternary ammonium salt catalyst. This protocol, which proceeds under classical liquid-solid phase-transfer conditions, gives access to unprecedented highly functionalized β2,2-amino acid derivatives with good enantioselectivities and in high yields, and further manipulations of these products have been carried out as well.
Trvalý link: https://hdl.handle.net/11104/0345495