Počet záznamů: 1
3'3' cyclic dinucleotides with an alkenylene
- 1.0580604 - ÚOCHB 2024 RIV eng P - Patentový dokument
Birkuš, Gabriel - Dejmek, Milan - Nencka, Radim - Otava, Tomáš - Šála, Michal - Páv, Ondřej
3'3' cyclic dinucleotides with an alkenylene.
2023. Vlastník: Ústav organické chemie a biochemie AV ČR, v. v. i. Datum udělení patentu: 17.08.2023. Číslo patentu: AU2021306597. Teritoriální ochrana: národní patent v zemi mimo EU ,mezinárodní patentová ochrana dle Smlouvy o patentové spolupráci.
Grant CEP: GA MŠMT(CZ) EF16_019/0000729
Institucionální podpora: RVO:61388963
Klíčová slova: STING * cyclic dinucleotide * oncology
Obor OECD: Medicinal chemistry
https://worldwide.espacenet.com/patent/search/family/071575129/publication/AU2021306597B2?q=AU2021306597B2
The present disclosure relates to 3'3' cyclic phosphonate dinucleotides of general formula (J), their pharmaceutically acceptable salts, their pharmaceutical composition and combinations of said substances and other medicaments or pharmaceuticals. The disclosure also relates to the use of said compounds for the treatment or prevention of diseases or conditions modifiable by STING protein modulation, such as cancer or viral, allergic and inflammatory diseases. In addition, these substances can be used as adjuvants in vaccines.
Trvalý link: https://hdl.handle.net/11104/0349367
Počet záznamů: 1