Non-shivering thermogenesis in skeletal muscle could compensate compromised thermogenesis in brown fat: Role of heart

0583466 - FGÚ 2024 RIV NL eng A - Abstrakt
Zouhar, Petr - Janovská, Petra - Bardová, Kristina - Otáhal, Jakub - Vrbacký, Marek - Mráček, Tomáš - Adamcová, Kateřina - Čajka, Tomáš - Drahota, Zdeněk - Stanić, Sara - Rustan, A. C. - Horáková, Olga - Houštěk, Josef - Rossmeisl, Martin - Kopecký, Jan
Non-shivering thermogenesis in skeletal muscle could compensate compromised thermogenesis in brown fat: Role of heart.
European Journal of Heart Failure. Roč. 25, Suppl.2 (2023), s. 437-437. ISSN 1388-9842. E-ISSN 1879-0844.
[Heart Failure 2023 and the World Congress on Acute Heart Failure. 20.05.2023-23.05.2023, Praha]
Grant CEP: GA MŠMT(CZ) LX22NPO5104
Institucionální podpora: RVO:67985823
Klíčová slova: non-shivering thermogenesis * skeletal muscle * brown adipose tissue * heart
Obor OECD: Cardiac and Cardiovascular systems
https://doi.org/10.1002/ejhf.2927

Impaired adrenergic NST in BAT of A/J mice could be compensatedby NST in skeletal muscle. Our findings indicate that muscle NST is inducible bycold and suggest that it may provide not only protection from cold, but also obesityresistance, more effectively than BAT. Heart may play an important strain-specificrole in regulation of muscular NST.
Trvalý link: https://hdl.handle.net/11104/0351437