Characterisation of the metabolome of Mycobacterium tuberculosis to identify new pathways and pathway holes
Master Thesis
2014
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University of Cape Town
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Abstract
Due to high incidence rates and the development of new drug-resistant or multidrug-resistant strains of TB, the development of new medicines and treatments for tuberculosis is a necessity. In order to develop these drugs, Mycobacterium tuberculosis (Mtb) needs to be studied more completely; this study performs a characterisation of the metabolome of Mtb and comparison across the phylogenetic profile to identify notable pathways.
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Wolfenden, K. 2014. Characterisation of the metabolome of Mycobacterium tuberculosis to identify new pathways and pathway holes. University of Cape Town.