Inclusion of Celecoxib in SBA 15 Mesoporous Silica Drug Loading and Release Property

Date

2015-06-22

Author

Yılmaz, Ayşen

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https://hdl.handle.net/11511/87108

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Inclusion of celecoxib in the SBA-15 mesoporous silica: drug loading and release property Eren, Zeynep Seda; Yılmaz, Ayşen; Department of Chemistry (2016) Mesoporous silica particles have been used to enhance the loading capacity of drugs into the support, increase the solubility of drug and control drug release. In this study, poorly water-soluble, nonsteroidal anti-inflammatory drug with relatively low bioavailability Celecoxib, was used as a model drug in order to determine the drug loading and release properties of silica particles. In order to synthesize SBA15 particles, hydrothermal synthesis method was used, SBA-15 samples were functionalized by post-g...
Inclusion of celecoxib in the MCM – 41 mesoporous silica: drug loading and release property Günaydin, Şahika; Yılmaz, Ayşen; Department of Chemistry (2014) Mesoporous silica particles have been used to enhance the biocompability of the drugs and provide control drug release. Celecoxib was chosen as a model drug which is poorly water soluble non-steroidal anti-inflammatory drug. In this study, in order to determine the morphology effect on the drug loading capacity of the silica particles and release properties of the drug, MCM-41 particles were synthesized with different particle size, pore volume and surface properties. MCM-41-1 and MCM-41-2 labeled particles...
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Citation Formats

A. Yılmaz, “Inclusion of Celecoxib in SBA 15 Mesoporous Silica Drug Loading and Release Property,” 2015, Accessed: 00, 2021. [Online]. Available: https://hdl.handle.net/11511/87108.