Ultracompact Three-Dimensional Tubular Conductivity Microsensors for Ionic and 
Biosensing Applications

Martinez-Cisneros, C. S.; Sanchez, S.; Schmidt, O. G.; Xi, Wang

doi:10.1021/nl500795k

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Ultracompact Three-Dimensional Tubular Conductivity Microsensors for Ionic and Biosensing Applications

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Sanchez, S.
Dept. Theory of Inhomogeneous Condensed Matter, Max Planck Institute for Intelligent Systems, Max Planck Society;
Institute for Integrative Nanosciences, Leibniz Institute for Solid State and Materials Research Dresden;

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Xi, Wang
Dept. Theory of Inhomogeneous Condensed Matter, Max Planck Institute for Intelligent Systems, Max Planck Society;

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Citation

Martinez-Cisneros, C. S., Sanchez, S., Schmidt, O. G., & Xi, W. (2014). Ultracompact Three-Dimensional Tubular Conductivity Microsensors for Ionic and Biosensing Applications. Nano Letters, 2219-2224. doi:10.1021/nl500795k.

Cite as: https://hdl.handle.net/11858/00-001M-0000-0025-C428-7

Abstract

We present ultracompact three-dimensional tubular structures integrating Au-based electrodes as impedimetric microsensors for the in-flow determination of mono- and divalent ionic species and HeLa cells. The microsensors show an improved performance of 2 orders of magnitude (limit of detection = 0.1 nM for KCl) compared to conventional planar conductivity detection systems integrated in microfluidic platforms and the capability to detect single HeLa cells in flowing phosphate buffered saline. These highly integrated conductivity tubular sensors thus open new possibilities for lab-in-a-tube devices for bioapplications such as biosensing and bioelectronics.