Modulation of a photoswitchable dual-color quantum dot containing a 
photochromic FRET acceptor and an internal standard.

Diaz, S. A.; Giordano, L.; Jovin, T. M.; Jares-Erijman, E. A.

doi:10.1021/nl301093s

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Modulation of a photoswitchable dual-color quantum dot containing a photochromic FRET acceptor and an internal standard.

MPG-Autoren

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Diaz, S. A.
Emeritus Group Laboratory of Cellular Dynamics, MPI for biophysical chemistry, Max Planck Society;

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Giordano, L.
Emeritus Group Laboratory of Cellular Dynamics, MPI for biophysical chemistry, Max Planck Society;

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Jovin, T. M.
Emeritus Group Laboratory of Cellular Dynamics, MPI for biophysical chemistry, Max Planck Society;

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Zitation

Diaz, S. A., Giordano, L., Jovin, T. M., & Jares-Erijman, E. A. (2012). Modulation of a photoswitchable dual-color quantum dot containing a photochromic FRET acceptor and an internal standard. Nano Letters, 12(7), 3537-3544. doi:10.1021/nl301093s.

Zitierlink: https://hdl.handle.net/11858/00-001M-0000-000F-A150-6

Zusammenfassung

Photoswitchable semiconductor nanoparticles, quantum dots (QDs), couple the advantages of conventional QDs with the ability to reversibly modulate the QD emission, thereby improving signal detection by rejection of background signals. Using a simple coating methodology with polymers incorporating a diheteroarylethene photochromic FRET acceptor as well as a spectrally distinct organic fluorophore, photoswitchable QDs were prepared that are small, biocompatible, and feature ratiometric dual emission. With programmed irradiation, the fluorescence intensity ratio can be modified by up to 100%.