Abstract
An efficient combination of MAO-N-catalyzed desymmetrization of cyclic meso-amines with Ugi-Smiles multicomponent chemistry produced optically pure N-aryl proline amides. This method represents the first report of a fully asymmetric Ugi-Smiles process.
Original language | English |
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Pages (from-to) | 941-944 |
Number of pages | 4 |
Journal | Organic and Biomolecular Chemistry |
Volume | 10 |
Issue number | 5 |
DOIs | |
Publication status | Published - 7 Feb 2012 |
Keywords
- Amides/chemical synthesis
- Amines/chemical synthesis
- Catalysis
- Cyclization
- Models, Molecular
- Proline/chemical synthesis
- Stereoisomerism
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CCDC 844264: Experimental Crystal Structure Determination
Znabet, A. (Contributor), Blanken, S. (Contributor), Janssen, E. (Contributor), De Kanter, F. J. J. (Contributor), Helliwell, M. (Contributor), Turner, N. J. (Contributor), Ruijter, E. (Contributor) & Orru, R. V. A. (Contributor), Unknown Publisher, 1 Jan 2012
DOI: 10.5517/ccxbjb2, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccxbjb2&sid=DataCite
Dataset