Mosaic chimeric viral vaccine particle
Abstract
The present invention describes compositions and methods for priming protective immunity in the presence of pre-existing maternal antibody. In some embodiments, the invention contemplates simultaneously masking vaccines to avoid antibody neutralization while targeting those vaccines to specific cell types in order to elicit an enhanced immune response. In other embodiments, vectors that recruit and activate specific antigen-presenting cells may further enhance the efficacy of those immune responses.
Subject
C07K 16/081C07K 16/1081
C07K 16/2851
A61K 2039/55522
C0ZK 2317/31
C07K 2317/622
C07K 2317/626
C07K 2317/76
C12N 2710/10343
C12N 2770/24334
C12N 2810/855
A61K 35/761
A61K 39/42
Collections
Citation
Mwangi, Waithaka; Waghela, Surya; Berghman, Luc (2019). Mosaic chimeric viral vaccine particle. United States. Patent and Trademark Office; Texas A&M University. Libraries. Available electronically from https : / /hdl .handle .net /1969 .1 /187390.