Manifestaciones neurológicas en pacientes con infección por Coronavirus (SARS-COV-2) durante la pandemia 2019-2020 una revisión analítica
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Fecha
2020
Autores
Pacheco Mosquera, Luis Fabián
Tapias Agamez, Manuel Alberto
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Ediciones Universidad Simón Bolívar
Facultad de Ciencias de la Salud
Facultad de Ciencias de la Salud
Resumen
Dado que los coronavirus no siempre permanecen confinados al sistema respiratorio, en determinadas condiciones pueden invadir distintos sistemas incluido el sistema nervioso, conllevando a la presentación de manifestaciones neurológicas diversas. Objetivos: Establecer la prevalencia de manifestaciones neurológicas en pacientes con infección por COVID-19 y su relación con las comorbilidades presentes en los sujetos del estudio. Materiales y métodos: Se realizó una revisión sistemática cuantitativa, a partir de los datos aportados por los estudios que hasta la fecha se han realizado en pacientes con COVID 19 encontrados en las bases de datos (MedRxiv, PUBMED, OVID, EMBASE, MEDLINE y SCOPUS. El tiempo de la revisión abarca desde el 01 de diciembre del 2019 hasta el 31 de mayo del 2020. Resultados: Mediante la estrategia de búsqueda PRISMA, se pudieron identificar 162 artículos siendo seleccionados para este estudio 58 de ellos. Conclusiones: La incidencia de manifestaciones neurológicas en pacientes con infección por COVID-19 resulta importante, por lo que se recomiendan todos los esfuerzos del personal médico para su detección oportuna, de tal forma que se brinden las opciones terapéuticas necesarias para impactar tanto en la mortalidad como en la discapacidad que puedan generar.
Since coronaviruses do not always remain confined to the respiratory system, under certain conditions they can invade different systems including the nervous system, leading to the presentation of various neurological manifestations. Objectives: To establish the prevalence of neurological manifestations in patients with COVID-19 infection and its relationship with the comorbidities present in the study subjects. Materials and methods: A quantitative systematic review was carried out, based on the data provided by the studies that have been carried out to date in patients with COVID 19 found in the databases (MedRxiv, PUBMED, OVID, EMBASE, MEDLINE and SCOPUS). The time during which the information in the databases was reviewed corresponds from December 1, 2019 to May 31, 2020. Results: Using the PRISMA search strategy, we were able to identify 162 articles. Finally, we had 58 articles for synthesis. Conclusions: Future epidemiological studies and case registries should give importance to the incidence of neurological manifestations, in addition to their pathogenic mechanisms, which leads to optimal therapeutic options that impact both mortality and disability.
Since coronaviruses do not always remain confined to the respiratory system, under certain conditions they can invade different systems including the nervous system, leading to the presentation of various neurological manifestations. Objectives: To establish the prevalence of neurological manifestations in patients with COVID-19 infection and its relationship with the comorbidities present in the study subjects. Materials and methods: A quantitative systematic review was carried out, based on the data provided by the studies that have been carried out to date in patients with COVID 19 found in the databases (MedRxiv, PUBMED, OVID, EMBASE, MEDLINE and SCOPUS). The time during which the information in the databases was reviewed corresponds from December 1, 2019 to May 31, 2020. Results: Using the PRISMA search strategy, we were able to identify 162 articles. Finally, we had 58 articles for synthesis. Conclusions: Future epidemiological studies and case registries should give importance to the incidence of neurological manifestations, in addition to their pathogenic mechanisms, which leads to optimal therapeutic options that impact both mortality and disability.
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Coronavirus, COVID-19, Encefalopatía, SARS-COV-2, ACV, Síndrome de Guillain Barre, Convulsión, Epilepsia, Cefalea, Encephalopathy, Stroke, Guillain Barre Syndrome, Seizure, Epilepsy, Headache