Zinc-α2-Glycoprotein Modulates AKT-Dependent Insulin Signaling in Human Adipocytes by Activation of the PP2A Phosphatase.

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Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.12530/21581

Title:	Zinc-α2-Glycoprotein Modulates AKT-Dependent Insulin Signaling in Human Adipocytes by Activation of the PP2A Phosphatase.
Authors:	Ceperuelo-Mallafré, Victòria Ejarque, Miriam Duran, Xavier Pachón, Gisela Vázquez-Carballo, Ana Roche, Kelly Núñez-Roa, Catalina Garrido-Sánchez, Lourdes Tinahones, Francisco J Vendrell, Joan Fernández-Veledo, Sonia View more
Mesh:	Adipocytes Adult Body Mass Index Cells, Cultured Enzyme Activation Female Glucose Glucose Transporter Type 1 Glucose Transporter Type 4 Humans Insulin Insulin Resistance Male Middle Aged Protein Phosphatase 2 Proto-Oncogene Proteins c-akt Seminal Plasma Proteins Signal Transduction Transcriptome View more
Issue Date:	2015
Citation:	PLoS ONE.2015;(10)6:e0129644
Abstract:	Evidence from mouse models suggests that zinc-α2-glycoprotein (ZAG) is a novel anti-obesity adipokine. In humans, however, data are controversial and its physiological role in adipose tissue (AT) remains unknown. Here we explored the molecular mechanisms by which ZAG regulates carbohydrate metabolism in human adipocytes.
PMID:	26068931
URI:	https://hdl.handle.net/20.500.12530/21581
Rights:	openAccess
Appears in Collections:	Fundaciones e Institutos de Investigación > IIS H. U. Clínico San Carlos > Artículos

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