Rheumatoid arthritis response to treatment across IgG1 allotype - anti-TNF incompatibility: a case-only study.

Montes, Ariana; Perez-Pampin, Eva; Navarro-Sarabia, Federico; Moreira, Virginia; de la Serna, Arturo Rodríguez; Magallares, Berta; Vasilopoulos, Yiannis; Sarafidou, Theologia; Fernández-Nebro, Antonio; Ordóñez, María Del Carmen; Narváez, Javier; Cañete, Juan D; Marquez, Ana; Pascual-Salcedo, Dora; Joven, Beatriz; Carreira, Patricia; Moreno-Ramos, Manuel J; Caliz, Rafael; Ferrer, Miguel Angel; Garcia-Portales, Rosa; Blanco, Francisco J; Magro, Cesar; Raya, Enrique; Valor, Lara; Alegre-Sancho, Juan J; Balsa, Alejandro; Martin, Javier; Plant, Darren; Isaacs, John; Morgan, Ann W; Barton, Anne; Wilson, Anthony G; Gómez-Reino, Juan J; Gonzalez, Antonio

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Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.12530/22173

Title:	Rheumatoid arthritis response to treatment across IgG1 allotype - anti-TNF incompatibility: a case-only study.
Authors:	Montes, Ariana Perez-Pampin, Eva Navarro-Sarabia, Federico Moreira, Virginia de la Serna, Arturo Rodríguez Magallares, Berta Vasilopoulos, Yiannis Sarafidou, Theologia Fernández-Nebro, Antonio Ordóñez, María Del Carmen Narváez, Javier Cañete, Juan D Marquez, Ana Pascual-Salcedo, Dora Joven, Beatriz Carreira, Patricia Moreno-Ramos, Manuel J Caliz, Rafael Ferrer, Miguel Angel Garcia-Portales, Rosa Blanco, Francisco J Magro, Cesar Raya, Enrique Valor, Lara Alegre-Sancho, Juan J Balsa, Alejandro Martin, Javier Plant, Darren Isaacs, John Morgan, Ann W Barton, Anne Wilson, Anthony G Gómez-Reino, Juan J Gonzalez, Antonio View more
Mesh:	Adalimumab Adult Antirheumatic Agents Arthritis, Rheumatoid Base Sequence Female Genotype Humans Immunoglobulin Allotypes Immunoglobulin G Infliximab Male Middle Aged Molecular Sequence Data Polymorphism, Single Nucleotide Treatment Outcome Tumor Necrosis Factor-alpha View more
Issue Date:	18-Mar-2015
Citation:	Arthritis Res. Ther..2015 Mar;(17):63
Abstract:	We have hypothesized that incompatibility between the G1m genotype of the patient and the G1m1 and G1m17 allotypes carried by infliximab (INX) and adalimumab (ADM) could decrease the efficacy of these anti-tumor necrosis factor (anti-TNF) antibodies in the treatment of rheumatoid arthritis (RA).
PMID:	25885039
URI:	https://hdl.handle.net/20.500.12530/22173
Rights:	openAccess
Appears in Collections:	Fundaciones e Institutos de Investigación > IIS H. General U. Gregorio Marañón > Artículos Fundaciones e Institutos de Investigación > IIS H. U. 12 de Octubre > Artículos Fundaciones e Institutos de Investigación > IIS H. U. La Paz > Artículos

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