Please use this identifier to cite or link to this item:
https://hdl.handle.net/20.500.12530/25774| Title: | Predictive value of vrk 1 and 2 for rectal adenocarcinoma response to neoadjuvant chemoradiation therapy: a retrospective observational cohort study. | |
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| Issue Date: | 2016 | |
| Citation: | BMC Cancer.2016 07;(16):519 | |
| Abstract: | Neoadjuvant chemoradiotherapy (NACRT) followed by surgical resection is the standard therapy for locally advanced rectal cancer. However, tumor response following NACRT varies, ranging from pathologic complete response to disease progression. We evaluated the kinases VRK1 and VRK2, which are known to play multiple roles in cellular proliferation, cell cycle regulation, and carcinogenesis, and as such are potential predictors of tumor response and may aid in identifying patients who could benefit from NACRT. | |
| PMID: | 27456229 | |
| URI: | https://hdl.handle.net/20.500.12530/25774 | |
| Rights: | openAccess | |
| Appears in Collections: | Fundaciones e Institutos de Investigación > IIS H. U. Clínico San Carlos > Artículos Fundaciones e Institutos de Investigación > IIS H. U. Ramón y Cajal > Artículos | |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| PMC4960836.pdf | 952.57 kB | Adobe PDF |  View/Open |
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