HLA-B*57 and IFNL4-related polymorphisms are associated with protection against HIV-1 disease progression in controllers.

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Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.12530/41305

Title:	HLA-B*57 and IFNL4-related polymorphisms are associated with protection against HIV-1 disease progression in controllers.
Authors:	Dominguez-Molina, B Tarancon-Diez, L Hua, S Abad-Molina, C Rodriguez-Gallego, E Machmach, K Vidal, F Tural, C Moreno, S Goñi, J M Ramírez de Arellano, E Del Val, M Gonzalez-Escribano, M F Del Romero, J Rodriguez, C Capa, L Viciana, P Alcamí, J Yu, X G Walker, B D Leal, Manuel Lichterfeld, M Ruiz-Mateos, E View more
Keywords:	HIV-controllers HLA-B*57 IFNL4 progression View more
Mesh:	Adult Cohort Studies Disease Progression Female Genetic Predisposition to Disease HIV Infections HIV-1 HLA-B Antigens Humans Interleukins Male Polymorphism, Single Nucleotide Young Adult View more
Issue Date:	2017
Citation:	Clin. Infect. Dis..2017 03;(64)5:621-628
Abstract:	HIV-1-controllers maintain HIV-1 viremia at low levels (normally <2000 HIV-RNA copies/mL) without antiretroviral treatment. However, some HIV-1-controllers have evidence of immunologic progression with marked CD4+T-cell decline. We investigated host genetic factors associated with protection against CD4+T-cell loss in HIV-1-controllers.
PMID:	27986689
URI:	https://hdl.handle.net/20.500.12530/41305
Rights:	openAccess
Appears in Collections:	Fundaciones e Institutos de Investigación > IIS H. U. Clínico San Carlos > Artículos Fundaciones e Institutos de Investigación > IIS H. U. Ramón y Cajal > Artículos

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