Publication:
Evaluation of nasal fluid beta-defensin 2 levels in children with allergic rhinitis

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Date
2017-06-01
Authors
DILEK, Fatih
EMIN, Ozkaya
Gultepe, BİLGE
Yazici, MEBRURE
Cakir, ERKAN
GEDIK, Ahmet Hakan
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Abstract
Aim: Knowledge about the role of the innate immune system in the pathogenesis of allergic diseases has been expanding in recent years. Defensins are antimicrobial peptides that are components of the innate immune system. Defensins have strong efficacy against bacterial, viral, and fungal infections. Moreover, they have regulatory functions in many physiologic processes such as antitumoral immunity, chemotaxis, inflammation, and wound healing. In this study, we aimed to investigate a-defensin 2 levels in the nasal fluids of children with allergic rhinitis.
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DILEK F., EMIN O., Gultepe B., Yazici M., Cakir E., GEDIK A. H. , -Evaluation of nasal fluid beta-defensin 2 levels in children with allergic rhinitis-, TURK PEDIATRI ARSIVI-TURKISH ARCHIVES OF PEDIATRICS, cilt.52, ss.79-84, 2017
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