Baloh R., Spooner J., (1981) Downbeat nystagmus: a type of central vestibular nystagmus. Neurology 31: 304-310.
Bensea S., Besta C., Buchholzb H., Wienera V., Schreckenbergerb M., Bartensteinb P., et al. (2006) 18F-fluorodeoxyglucose hypometabolism in cerebellar tonsil and flocculus in downbeat nystagmus. NeuroReport 17: 599-603.
Benussi A., Koch G., Cotelli M., Padovani A., Borroni B., (2015) Cerebellar transcranial direct current stimulation in patients with ataxia: a double-blind, randomized, sham-controlled study. Mov Disord 30: 1701-1705.
Bodranghien F., Bastian A., Casali C., Hallett M., Louis E., Manto M., et al. (2016) Consensus paper. Revisiting the symptoms and signs of cerebellar syndrome. Cerebellum 15: 369-391. DOI 10.1007/s12311-015-0687-3.
Braitenberg V., Atwood R., (1958) Morphological observations on the cerebellar cortex. J Comp Neurol 109: 1-33.
Camargo F., Erickson R., Garver W., Hossain G., Carbone P., Heidenreich R., et al. (2001) Cyclodextrins in the treatment of a mouse model of Niemann-Pick C disease. Life Sci 70: 131-142.
Carrillo F., Palomar F., Conde V., Diaz-Corrales F., Porcacchia P., Fernández-Del-Olmo M., et al. (2013) Study of cerebello-thalamocortical pathway by transcranial magnetic stimulation in Parkinson's disease. Brain Stimul 6: 582-589.
Claassen J., Teufel J., Kalla R., Spiegel R., Strupp M., (2013) Effects of dalfampridine on attacks in patients with episodic ataxia type 2: an observational study. J Neurol 260: 668-669.
Deuschl G., Toro C., Zeffiro T., Massaquoi S., Hallett M., (1996) Adaptation motor learning of arm movements in patients with cerebellar disease. J Neurol Neurosurg Psychiatry 60: 515-519.
Dow R., Moruzzi G., (1958) The Physiology and Pathology of the Cerebellum. University of Minnesota Press: Minneapolis.
Galea J., Jayaram G., Ajagbe L., Celnik P., (2009) Modulation of cerebellar excitability by polarity-specific noninvasive direct current stimulation. J Neurosci 29: 9115-9122.
Galliano E., De Zeeuw C., (2014) Questioning the cerebellar doctrine. Prog Brain Res 210: 59-77.
Giordano I., Bogdanow M., Jacobi H., Jahn K., Minnerop M., Schoels L., et al. (2013) Experience in a short-term trial with 4-aminopyridine in cerebellar ataxia. J Neurol 260: 2175-2176.
Glasauer S., Hoshi M., Kempermann U., Eggert T., Büttner U., (2003) Three-dimensional eye position and slow phase velocity in humans with downbeat nystagmus. J Neurophysiol 89: 338-354.
Glasauer S., Kalla R., Buttner U., Strupp M., Brandt T., (2005) 4-Aminopyridine restores visual ocular motor function in upbeat nystagmus. J Neurol Neurosurg Psychiatry 76: 451-453.
Greenberg M., (2006) Handbook of Neurosurgery, 6th edition. New York: Thieme Medical Publisher.
Grimaldi G., Argyropoulos G., Bastian A., Cortes M., Davis N., Edwards D., et al. (2016) Cerebellar transcranial direct current stimulation (ctDCS): a novel approach to understanding cerebellar function in health and disease. Neuroscientist 22: 83-97.
Grimaldi G., Argyropoulos G.P., Boehringer A., Celnik P., Edwards M.J., Ferrucci R., et al. (2014a) Non-invasive cerebellar stimulation-a consensus paper. Cerebellum 13: 121-138.
Grimaldi G., Oulad Ben Taib N., Manto M., Bodranghien F., (2014b) Marked reduction of cerebellar deficits in upper limbs following transcranial cerebello-cerebral DC stimulation: tremor reduction and re-programming of the timing of antagonist commands. Front Syst Neurosci 8: 9.
Hacke W., Kaste M., Bluhmki E., Brozman M., Dávalos A., Guidetti D., et al. (2008) Thrombolysis with alteplase 3 to 4.5 hours after acute ischemic stroke. N Engl J Med 359: 1317-1329.
Ienaga Y., Mitoma H., Kubota K., Morita S., Mizusawa H., (2006) Dynamic imbalance in gait ataxia. Characteristics of plantar pressure measurement. J Neurol Sci 246: 53-57.
Ilg W., Bastian A., Boesch S., Celnik P., Claaßen J., Feil K., et al. (2014) Consensus paper: Management of degenerative cerebellar disorders. Cerebellum 13: 248-268
Ilg W., Brötz D., Burkard S., Giese M, Schöls L., Synofzik M., (2010) Long-term effects of coordinative training in degenerative cerebellar disease. Mov Disord 25: 2239-2246.
Ilg W., Synofzik M., Brotz D., Burkard S., Giese M., Schols L., (2009) Intensive coordinative training improves motor performance in degenerative cerebellar disease. Neurology 73: 1823-1830.
Ishikawa T., Tomatsu S., Lee J., Hoffman D., Kakei S., (2014) Releasing dentate nucleus cells from Purkinje cell inhibition generates output from the cerebrocerebellum. PLoS One 9: e108774.
Ito M., (2006) Cerebellar circuitry as a neural machine. Prog Neurobiol 78: 272-303.
Ivry R., (1997) Cerebellar timing systems. Int Rev Neurobiol 41: 555-573.
Jaarsma D., Ruigrok T., Caff- R., Cozzari C., Levey A., Mugnaini E., et al. (1997) Cholinergic innervation and receptors in the cerebellum. Prog Brain Res 114: 67-96.
Jauss M., Krieger D., Hornig C., Schramm J., Busse O., (1992) Surgical and medical management of patients with massive cerebellar infarctions: results of the German-Austrian Cerebellar Infarction Study. J Neurol 246: 257-264.
Jayaram G., Tang B., Pallegadda R., Vasudevan E., Celnik P., Bastian A., (2012) Modulating locomotor adaptation with cerebellar stimulation. J Neurophysiol 107: 2950-2957.
Jen J., Graves T., Hess E., Hanna M., Griggs R., Baloh R., (2007) Primary episodic ataxias: diagnosis, pathogenesis and treatment. Brain 130: 2484-2493.
Jensen M., St Louis E., (2005) Management of acute cerebellar stroke. Arch Neurol 62: 537-544.
Kalla R., Glasauer S., Büttner U., Brandt T., Strupp M., (2007) 4-Aminopyridine restores vertical and horizontal neural integrator function in downbeat nystagmus. Brain 130: 2441-2445.
Kalla R., Glasauer S., Schautzer F., Lehnen N., Büttner U., Strupp U., et al. (2004) 4-Aminopyridine improves downbeat nystagmus, smooth pursuit, and VOR gain. Neurology 62: 1228-1229.
Kawato M., Furukawa K., Suzuki R., (1987) A hierarchical neural network model for control and learning of voluntary movement. Biol Cybern 57: 169-185.
Llinas R.R., (2009) Inferior olive oscillation as temporal basis for motricity and oscillatory reset as the motor error correction. Neuroscience 162: 797-804.
Lu J., Wang X., Huang Y., Qiu Y., Peng Y., (2015) GABAergic neurons in cerebellar interposed nucleus modulate cellular and humoral immunity via hypothalamic and sympathetic pathways. J Neuroimmunol 283: 30-38.
Manto M., (2002) Clinical signs of cerebellar disorders. In: Manto M., Pandolfo M., (eds), The Cerebellum and its Disorders. Cambridge, UK: Cambridge University Press, pp. 97-120.
Manto M., (2008) The cerebellum, cerebellar disorders, and cerebellar research. Two centuries of discoveries. Cerebellum 7: 505-516.
Manto M., Bower J., Conforto A., Delgado-García J., da Guarda S., Gerwig M., et al. (2012) Consensus paper: roles of the cerebellum in motor control-the diversity of ideas on cerebellar involvement in movement. Cerebellum 11: 457-487.
Marti S., Straumann D., Glasauer S., (2005) The origin of downbeat nystagmus: an asymmetry in the distribution of on-directions of vertical gaze-velocity Purkinje cells. Ann NY Acad Sci 1039: 548-553.
Matsushita K., Wakamori M., Rhyu I., Arii T., Oda S., Mori Y., et al. (2002) Bidirectional alterations in cerebellar synaptic transmission of tottering and rolling Ca2+ channel mutant mice. J Neurosci 22: 4388-4398.
Mitoma H., Hadjivassiliou M., Honnorat J., (2015) Guidelines for treatment of immune-mediated cerebellar ataxias. Cerebellum Ataxias 2: 14.
Mitoma H., Adhikari K., Aeschlimann D., Chattopadhyay P., Hadjivassiliou M., Hampe C., et al. (2016) Consensus paper: neuroimmune mechanisms of cerebellar ataxias. Cerebellum 15: 213-232. DOI 10.1007/s12311-015-0664-x.
Miyai I., Ito M., Hattori N., Mihara M., Hatakenaka M., Yagura H., et al. (2012) Cerebellar ataxia rehabilitation trial in degenerative cerebellar diseases. Neurorehabil Neural Repair 26: 515-522.
Morgenstern L., Hemphill J. III, Anderson C., Becker K., Broderick J., Connolly E. Jr, et al. (2010) Guidelines for the management of spontaneous intracerebral hemorrhage: a guide line for healthcare professionals from the American Heart Association/American Stroke Association. Stroke 41: 2108-2129.
Nie S., Chen G., Cao X., Zhang Y., (2014) Cerebrotendinous xanthomatosis: a comprehensive review of pathogenesis, clinical manifestations, diagnosis, and management. Orphanet J Rare Dis 9: 179.
Nixon M., Ambekar S., Zhang S., Markham C., Akbarian-Tefaghi H., Morrow K., et al. (2014) Traumatic injury to posterior fossa. Neurol Clin 32: 943-955.
Nusca S., Canterini S., Palladino G., Bruno F., Mangia F., Erickson R., et al. (2014) A marked paucity of granule cells in the developing cerebellum of the Npc1(-/-) mouse is corrected by a single injection of hydroxypropyl-β-cyclodextrin. Neurobiol Dis 70: 117-126.
Ovsepian S., Friel D., (2008) The leaner P/Q-type calcium channel mutation renders cerebellar Purkinje neurons hyper-excitable and eliminates Ca2+-Na+ spike bursts. Eur J Neurosci 27: 93-103.
Patterson M., Vecchio D., Prady H., Abel L., Wraith J.E., (2007) Miglustat for treatment of Nieman-Pick C disease: a randomized controlled study. Lancet Neurol 6: 765-772.
Pierrot-Deseilligny C., Milea D., (2005) Vertical nystagmus: clinical facts and hypotheses. Brain 128: 1237-1246.
Ristori G., Romano S., Visconti A., Cannoni S., Spadaro M., Frontali M., et al. (2010) Riluzole in cerebellar ataxia: a randomized, double-blind, placebo-controlled pilot trial. Neurology 74: 839-845.
Romano S., Coarelli G., Marcotulli C., Leonardi L., Piccolo F., Spadaro M., et al. (2015) Riluzole in patients with hereditary cerebellar ataxia: a randomised, double-blind, placebo-controlled trial. Lancet Neurol 14: 985-991.
Scalzo S., Bowden S., Ambrose M., Whelan G., Cook M., (2015) Wernicke-Korsakoff syndrome not related to alcohol use: a systematic review. J Neurol Neurosurg Psychiatry 86: 1362-1368.
Schniepp R., Wuehr M., Neuhaeusser M., Kathrin Benecke A., Adrion C., Brandt T., et al. (2012) 4-Aminopyridine and cerebellar gait: a retrospective case series. J Neurol 259: 2491-2493.
Stemmler T., Lesuisse E., Pain D., Dancis A., (2010) Frataxin and mitochondrial FeS cluster biogenesis. J Biol Chem 285: 26737-26743.
Strupp M., Kalla R., Claassen J., Adrion C., Mansmann U., Klopstock T., et al. (2011) A randomized trial of 4-aminopyridine in EA2 and related familial episodic ataxias. Neurology 77: 269-275.
Strupp M., Kalla R., Dichgans M., Freilinger T., Glasauer S., Brandt T., (2004) Treatment of episodic ataxia type 2 with the potassium channel blocker 4-aminopyridine. Neurology 62: 1623-1625.
Strupp M., Kalla R., Glasauer S., Wagner J., Hufner K., Jahn K., et al. (2008) Aminopyridines for the treatment of cerebellar and ocular motor disorders. Prog Brain Res 171: 535-541.
Strupp M., Schüler O., Krafczyk S., Jahn K., Schautzer F., Büttner U., et al. (2003) Treatment of downbeat nystagmus with 3,4-diaminopyridine. A placebo-controlled study. Neurology 61: 165-170.
Strupp M., Teufel J., Habs M., Feuerecker R., Muth C., van deWarrenburg B., et al. (2013) Effects of acetyl-DL-leucine in patients with cerebellar ataxia: a case series. J Neurol 260: 2556-2561.
Tan H., Collewjin H., (1991) Cholinergic modulation of optokinetic and vestibulo-ocular responses: a study with microinjections in the flocculus of the rabbit. Exp Brain Res 85: 475-481.
Tsunemi T., Ishikawa K., Tsukui K., Sumi T., Kitamura K., Mizusawa H., (2010) The effect of 3,4-diaminopyridine on the patients with hereditary pure cerebellar ataxia. J Neurol Sci 292: 81-84.
Ugawa Y., Uesaka Y., Terao Y., Hanajima R., Kanazawa I., (1995) Magnetic stimulation over the cerebellum in humans. Ann Neurol 37: 703-713.
Velázquez-Pérez L., Rodríguez-Chanfrau J., García-Rodríguez J., Sánchez-Cruz G., Aguilera-Rodríguez R., Rodríguez-Labrada R., et al. (2011) Oral zinc sulphate supplementation for six months in SCA2 patients: a randomized, double-blind, placebo-controlled trial. Neurochem Res 36: 1793-1800.
Vibert N., Vidal P., (2001) In vitro effects of acetyl-DL-leucine (Tanganil) on central vestibular neurons and vestibulo-ocular networks of the guinea-pig. Eur J Neurosci 13: 735-748.
Vite C., Bagel J., Swain G., Prociuk M., Sicora T., Stein V., et al. (2015) Intracisternal cyclodextrin prevents cerebellar dysfunction and Purkinje cell death in feline Niemann-Pick type C1 disease. Sci Transl Med 7: 276ra26.
Walter J., Alvina K., Womack M., Chevez C., Khodakhah K., (2006) Decreases in the precision of Purkinje cell pacemaking cause cerebellar dysfunction and ataxia. Nat Neurosci 9: 389-397.
Weier K., Banwell B., Cerasa A., Collins D., Dogonowski A., Lassmann H., et al. (2015) The role of the cerebellum in multiple sclerosis. Cerebellum 14: 364-374.
Wijdicks E., Sheth K., Carter B., Greer D., Kasner S., Kimberly W., et al. (2014) Recommendations for the management of cerebral and cerebellar infarction with swelling. A statement for healthcare professionals from the American Heart Association/American Stroke Association. Stroke 45: 1222-1238.
Womack M., Chevez C., Khodakhah K., (2004) Calcium-activated potassium channels are selectively coupled to P/Q-type calcium channels in cerebellar Purkinje neurons. J Neurosci 24: 8818-8822.
Womack M., Khodakhaha K., (2003) Somatic and dendritic small-conductance calcium-activated potassium channels regulate the output of cerebellar Purkinje neurons. J Neurosci 23: 2600-2607.
Yabe I., Sasaki H., Yamashita I., Takei A., Tashiro K., (2001) Clinical trial of acetazolamide in SCA6, with assessment using the Ataxia Rating Scale and body stabilometry. Acta Neurol Scand 104: 44-47.
Yokota T., Shiojiri T., Gotoda T., Arita M., Arai H., Ohga T., et al. (1997) Friedrich-like ataxia with retinitis pigmentosa caused by the His 101 Gln mutation of the alpha-tocopherol transfer protein gene. Ann Neurol 41: 826-832.
Zee D., Yamazaki A., Butler P., Gücer G., (1981) Effects of ablation of flocculus and paraflocculus of eye movements in primate. J Neurophysiol 46: 878-899.
Zesiewicz T., Greenstein P., Sullivan K., Wecker L., Miller A., Jahan I., et al. (2012) A randomized trial of varenicline (Chantix) for the treatment of spinocerebellar ataxia type 3. Neurology 78: 545-550.
