Identificador para citar o enlazar este ítem: https://hdl.handle.net/20.500.13003/18793
Does early onset asthma increase childhood obesity risk? A pooled analysis of 16 European cohorts
Identificadores
eISSN: 1399-3003
WOS ID: 000452391500012
Scopus EID: 2-s2.0-85054464320
PMID: 30209194
Embase PUI: L2002034412
Compartir
Estadísticas
Ver estadísticas de uso de este ítemMetadatos
Ver el registro Dublin Core del ítemAutor
Contreras, Zuelma A.; Chen, Zhanghua; Roumeliotaki, Theano; Annesi-Maesano, Isabella; Baïz, Nour; von Berg, Andrea; Bergström, Anna; Crozier, Sarah; Duijts, Liesbeth; Ekström, Sandra; Eller, Esben E.; Fantini, Maria Pia; Kjaer, Henrik Fomsgaard; Forastiere, Francesco; Gerhard, Beatrix; Gori, Davide; Harskamp-van Ginkel, Margreet W.; Heinrich, Joachim; Iñiguez, Carmen; Inskip, Hazel; Keil, Thomas; Kogevinas, Manolis; Lau, Susanne; Lehmann, Irina; Maier, Dieter; van Meel, Evelien R; Mommers, Monique; Murcia, Mario; Porta, Daniela; Smit, Henriëtte A; Standl, Marie; Stratakis, Nikos; Sunyer, Jordi; Thijs, Carel; Torrent Quetglas, Maties ; Vrijkotte, Tanja G M; Wijga, Alet H; Berhane, Kiros; Gilliland, Frank; Chatzi, LedaFecha de publicación
2018-09Tipo de documento
research articleCitación
Contreras ZA, Chen Z, Roumeliotaki T, Annesi-Maesano I, Baïz N, von Berg A, et al. Does early onset asthma increase childhood obesity risk? A pooled analysis of 16 European cohorts. Eur Respir J. 2018 Sep;52(3).Resumen
The parallel epidemics of childhood asthma and obesity over the past few decades have spurred research into obesity as a risk factor for asthma. However, little is known regarding the role of asthma in obesity incidence. We examined whether early-onset asthma and related phenotypes are associated with the risk of developing obesity in childhood.This study includes 21 130 children born from 1990 to 2008 in Denmark, France, Germany, Greece, Italy, The Netherlands, Spain, Sweden and the UK. We followed non-obese children at 3-4 years of age for incident obesity up to 8 years of age. Physician-diagnosed asthma, wheezing and allergic rhinitis were assessed up to 3-4 years of age.Children with physician-diagnosed asthma had a higher risk for incident obesity than those without asthma (adjusted hazard ratio (aHR) 1.66, 95% CI 1.18-2.33). Children with active asthma (wheeze in the last 12 months and physician-diagnosed asthma) exhibited a higher risk for obesity (aHR 1.98, 95% CI 1.31-3.00) than those without wheeze and asthma. Persistent wheezing was associated with increased risk for incident obesity compared to never wheezers (aHR 1.51, 95% CI 1.08-2.09).Early-onset asthma and wheezing may contribute to an increased risk of developing obesity in later childhood.
Versión del editor
https://doi.org/10.1183/13993003.00504-2018MeSH
ChildAsthma
Humans
Child, Preschool
Rhinitis, Allergic
Pediatric Obesity
Phenotype
Male
Europe
Female
Risk Factors
Age of Onset
Cohort Studies
Respiratory Sounds
DeCS
Estudios de CohortesEdad de Inicio
Femenino
Europa (Continente)
Obesidad Pediátrica
Masculino
Rinitis Alérgica
Factores de Riesgo
Preescolar
Humanos
Asma
Fenotipo
Niño
Ruidos Respiratorios